This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Myc (Phospho-Thr358) Antibody
catalog :
MBS856642
quantity :
0.05 mg
price :
225 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
product information
catalog number :
MBS856642
products type :
Antibody
products full name :
Myc (Phospho-Thr358) Antibody
products short name :
Myc
other names :
myc proto-oncogene protein; Myc proto-oncogene protein; myc proto-oncogene protein; proto-oncogene c-Myc; transcription factor p64; class E basic helix-loop-helix protein 39; avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog; myc-related translation/localization regulatory factor; v-myc avian myelocytomatosis viral oncogene homolog; Class E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64
products gene name :
Myc
other gene names :
MYC; MYC; MRTL; MYCC; c-Myc; bHLHe39; BHLHE39; bHLHe39
uniprot entry name :
MYC_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
454
specificity :
Myc (phospho-Thr358) antibody detects endogenous levels of Myc only when phosphorylated at threonine 358.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
50ug/50ul
storage stability :
Store at -20 degree C for 1 year
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500~1:1000, IHC: 1:50~1:100, IF:1:100~1:200
other info2 :
Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Myc around the phosphorylation site of threonine 358 (R-R-TP-H-N). Pathway: MAPK, Chromatin/Transcription, CellCycle, Cancer/Apoptosis
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
Baudino T A, et al. (2001) Mol Cell Biol. 21: 691-702. Blackwood E M, et al. (1991) Science. 251:1211-1217. Henriksson M, et al. (1996) Adv Cancer Res. 68: 109-182. Grandori C, et al. (2000) Annu Rev Cell Dev Biol. 16: 653-699.
ncbi gi num :
71774083
ncbi acc num :
NP_002458.2
ncbi gb acc num :
NM_002467.4
uniprot acc num :
P01106
ncbi mol weight :
50,565 Da
ncbi pathways :
Acute Myeloid Leukemia Pathway 83117!!Acute Myeloid Leukemia Pathway 529!!Apoptosis Pathway 198797!!Bladder Cancer Pathway 83115!!Bladder Cancer Pathway 527!!C-MYB Transcription Factor Network Pathway 138073!!C-MYC Pathway 169344!!CD40/CD40L Signaling Pathway 138061!!Cell Cycle Pathway 530733!!Cell Cycle, Mitotic Pathway 105765
ncbi summary :
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
size :
0.05 mg
price :
225 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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