product summary
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company name :
MyBioSource
product type :
antibody
product name :
CREM Antibody
catalog :
MBS856202
quantity :
0.1 mg
price :
215 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, enzyme immunoassay
more info or order :
product information
catalog number :
MBS856202
products type :
Antibody
products full name :
CREM Antibody
products short name :
CREM
products name syn :
CREM-alpha; cAMP-responsive element modulator; cAMP-responsive element modulator; alpha isoform CREM; CREM-beta; cAMP-responsive element modulator; cAMP-responsive element modulator; beta isoform CREM-BCEFGIalpha; Tau
other names :
cAMP-responsive element modulator isoform 23; cAMP-responsive element modulator; cAMP-responsive element modulator; CREM 2beta-a protein; CREM 2alpha-b protein; cAMP response element modulator; inducible cAMP early repressor ICER; cAMP responsive element modulator; Inducible cAMP early repressor; ICER
products gene name :
CREM
other gene names :
CREM; CREM; ICER; CREM-2; hCREM-2; ICER
uniprot entry name :
CREM_HUMAN
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
179
specificity :
CREM antibody detects endogenous levels of total CREM protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20 degree C for 1 year
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
WB: 1:500~1:1000, ELISA: 1:20000
other info2 :
Immunogen: The antiserum was produced against synthesized peptide derived from internal of human CREM. Pathway: Transcription
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
Masquilier D., Cell Growth Differ. 4:931-937(1993). Meyer T.E., Nucleic Acids Res. 20:6106-6106(1992). Fujimoto T., J. Biochem. 115:298-303(1994). ------------------------------------------------------------------------------------------------------------------------------------------
ncbi gi num :
389616125
ncbi acc num :
NP_001254491.1
ncbi gb acc num :
NM_001267562.1
uniprot acc num :
Q03060
ncbi mol weight :
26,269 Da
ncbi pathways :
Adrenergic Signaling In Cardiomyocytes Pathway (908257); Adrenergic Signaling In Cardiomyocytes Pathway (909696); HTLV-I Infection Pathway (373901); HTLV-I Infection Pathway (373889); SIDS Susceptibility Pathways (198901); Selenium Metabolism And Selenoproteins Pathway (198846)
ncbi summary :
This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008]
uniprot summary :
CREM: a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. An important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative splice isoforms allow this protein to exert spatial and temporal specificity to cAMP responsiveness. Twentyeight alternatively spliced isoforms of the human protein have been described, with some of them functioning as activators and some as repressors of transcription. Protein type: Transcription factor; DNA-binding. Chromosomal Location of Human Ortholog: 10p11.21. Cellular Component: transcription factor complex; cytoplasm; nucleus. Molecular Function: protein binding; DNA binding; cAMP response element binding protein binding; transcription factor activity. Biological Process: response to cAMP; transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development; glycosphingolipid metabolic process; spermatogenesis; positive regulation of transcription from RNA polymerase II promoter; circadian regulation of gene expression; cell differentiation; signal transduction; negative regulation of transcription, DNA-dependent
size1 :
0.1 mg
price1 :
215 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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