product summary
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company name :
MyBioSource
product type :
antibody
product name :
NOX5 Antibody
catalog :
MBS856080
quantity :
0.1 mg
price :
215 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
product information
catalog number :
MBS856080
products type :
Antibody
products full name :
NOX5 Antibody
products short name :
NOX5
products name syn :
NADPH oxidase 5
other names :
NADPH oxidase 5 isoform 2; NADPH oxidase 5; NADPH oxidase 5; NADPH oxidase, EF-hand calcium binding domain 5
products gene name :
NOX5
other gene names :
NOX5; NOX5
uniprot entry name :
NOX5_HUMAN
host :
Rabbit
reactivity :
Human
sequence length :
737
specificity :
NOX5 antibody detects endogenous levels of total NOX5 protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20 degree C for 1 year
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
WB: 1:500~1:1000, ELISA: 1:40000
other info1 :
Reactivity Note: Human (Identities = 100%, Positives = 100%)
other info2 :
Immunogen: The antiserum was produced against synthesized peptide derived from C-terminal of human NOX5. Pathway: Translation
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
Banfi B., J. Biol. Chem. 276:37594-37601(2001). Jikuya H., Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases. Kawahara T., J. Biol. Chem. 280:31859-31869(2005).
ncbi gi num :
296278227
ncbi acc num :
NP_001171708.1
ncbi gb acc num :
NM_001184779.1
uniprot acc num :
Q96PH1
ncbi mol weight :
83,109 Da
ncbi summary :
This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
uniprot summary :
NOX5: Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis. Isoform v2 and isoform v5 are involved in endothelial generation of reactive oxygen species (ROS), proliferation and angiogenesis and contribute to endothelial response to thrombin. 6 isoforms of the human protein are produced by alternative splicing. Protein type: EC 1.6.3.-; Oxidoreductase; Membrane protein, integral; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 15q23. Cellular Component: endoplasmic reticulum; integral to membrane. Molecular Function: protein binding; FAD binding; superoxide-generating NADPH oxidase activity; heme binding; calcium ion binding; hydrogen ion channel activity; NADP binding. Biological Process: cell proliferation; proton transport; regulation of fusion of sperm to egg plasma membrane; apoptosis; endothelial cell proliferation; cytokinesis; regulation of proton transport; angiogenesis; cytokine secretion; superoxide release
size1 :
0.1 mg
price1 :
215 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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