EPHA7 (Phospho-Tyr791) Antibody | MyBioSource MBS856068 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

EPHA7 (Phospho-Tyr791) Antibody

catalog :

MBS856068

quantity :

0.1 mg

price :

215 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS856068

products type :

Antibody

products full name :

EPHA7 (Phospho-Tyr791) Antibody

products short name :

EPHA7

products name syn :

EHK-3; EHK3; EK11; EPH homology kinase 3; Eph homology kinase-3; EPH receptor A7; EPH-like kinase 11; EPHA7; ephrin receptor EphA7; Ephrin type-A receptor 7; HEK11; receptor protein-tyrosine kinase HEK11; tyrosine-protein kinase receptor EHK-3

other names :

ephrin type-A receptor 7 isoform 2; Ephrin type-A receptor 7; ephrin type-A receptor 7; EPH-like kinase 11; EPH homology kinase 3; Eph homology kinase-3; receptor protein-tyrosine kinase HEK11; tyrosine-protein kinase receptor EHK-3; EPH receptor A7; EPH homology kinase 3; EHK-3; EPH-like kinase 11; EK11; hEK11

products gene name :

EPHA7

other gene names :

EPHA7; EPHA7; EHK3; EK11; EHK-3; HEK11; EHK3; HEK11; EHK-3; EK11; hEK11

uniprot entry name :

EPHA7_HUMAN

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

993

specificity :

EPHA7 (Phospho-Tyr791) antibody detects endogenous levels of EPHA7only when phosphorylated at tyrosine 791.

purity :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation

form :

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

storage stability :

Store at -20 degree C for 1 year

tested application :

Western Blot (WB), ELISA (EIA)

app notes :

WB: 1:500~1:1000, ELISA: 1:10000

other info2 :

Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human EPHA7around the phosphorylation site of tyrosine 791. All Sites: Human: Tyr791; Mouse: Tyr791; Rat: Tyr791. Pathway: Phospho-specific

products categories :

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

products references :

Fox G.M., Oncogene 10:897-905(1995). Mungall A.J., Nature 425:805-811(2003). Mungall A.J., Nature 425:805-811(2003).

ncbi gi num :

568599847

ncbi acc num :

NP_001275558.1

ncbi gb acc num :

NM_001288629.1

uniprot acc num :

Q15375

ncbi mol weight :

50,521 Da

ncbi pathways :

Axon Guidance Pathway (83065); Axon Guidance Pathway (476); Axon Guidance Pathway (105688); Developmental Biology Pathway (477129); EPH-Ephrin Signaling Pathway (1016174); EPH-ephrin Mediated Repulsion Of Cells Pathway (1016178); EPHA Forward Signaling Pathway (138041); EPHA-mediated Growth Cone Collapse Pathway (1016175); EphrinA-EPHA Pathway (137942)

ncbi summary :

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

uniprot summary :

EphA7: a widely-expressed receptor tyrosine kinase of the Eph family. Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A2, -A3, -A4 and -A5. Contains 1 sterile alpha motif (SAM) and two fibronectin type III domains. Protein type: Membrane protein, integral; Kinase, protein; Protein kinase, TK; EC 2.7.10.1; Protein kinase, tyrosine (receptor); TK group; Eph family. Chromosomal Location of Human Ortholog: 6q16.1. Cellular Component: postsynaptic membrane; cell soma; integral to plasma membrane; dendrite; plasma membrane; neuromuscular junction. Molecular Function: protein binding; ephrin receptor binding; GPI-linked ephrin receptor activity; chemorepellent activity; protein-tyrosine kinase activity; axon guidance receptor activity; ATP binding. Biological Process: axon guidance; peptidyl-tyrosine phosphorylation; branching morphogenesis of a nerve; regulation of protein amino acid autophosphorylation; negative chemotaxis; regulation of caspase activity; regulation of cell-cell adhesion; positive regulation of neuron apoptosis; ephrin receptor signaling pathway; brain development; phosphorylation; regulation of peptidyl-tyrosine phosphorylation; retinal ganglion cell axon guidance

size1 :

0.1 mg

price1 :

215 USD

more info or order :

MyBioSource product webpage