product summary
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company name :
MyBioSource
product type :
antibody
product name :
ABCA3 Antibody
catalog :
MBS855986
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
more info or order :
product information
catalog number :
MBS855986
products type :
Antibody
products full name :
ABCA3 Antibody
products short name :
ABCA3
other names :
ATP-binding cassette sub-family A member 3; ATP-binding cassette sub-family A member 3; ATP-binding cassette sub-family A member 3; ABC transporter 3; ABC-C transporter; ATP-binding cassette transporter 3; ATP-binding cassette, sub-family A (ABC1), member 3; ABC-C transporter; ATP-binding cassette transporter 3; ATP-binding cassette 3
products gene name :
ABCA3
other gene names :
ABCA3; ABCA3; ABC3; ABC-C; SMDP3; LBM180; EST111653; ABC3; ATP-binding cassette 3
uniprot entry name :
ABCA3_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human
sequence length :
1704
form :
Lyophilized ABCA3 antibody purified by protein A column containing 0.02% NaN3
concentration :
100ug/200ul
tested application :
Western Blot (WB)
app notes :
ELISA titer: 1:10,000-1:80,000. Western blot analysis: 1:1,000-1:2,000. Optimal dilutions/concentrations should be determined by the end user.
other info1 :
Source Note: Rabbit polyclonal ABCA3 (1) antibody was raised against a recombinate human ABCA3 protein 38-209aa (BC062779). Reactivity Note: Predicted: Mouse, Rat; Not yet tested in other species.
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
(1) Strausberg,R.L., Feingold,E.A., Grouse,L.H., et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
ncbi gi num :
116734710
ncbi acc num :
BC062779
ncbi gb acc num :
NM_001089.2
ncbi mol weight :
24,002 Da
ncbi pathways :
ABC Transporters Pathway (83035); ABC Transporters Pathway (436); ABC-family Proteins Mediated Transport Pathway (106573); ABCA Transporters In Lipid Homeostasis Pathway (477112); Transmembrane Transport Of Small Molecules Pathway (106572)
ncbi summary :
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The full transporter encoded by this gene may be involved in development of resistance to xenobiotics and engulfment during programmed cell death. [provided by RefSeq, Jul 2008]
uniprot summary :
ABCA3: Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol. Defects in ABCA3 are the cause of pulmonary surfactant metabolism dysfunction type 3 (SMDP3); also called pulmonary alveolar proteinosis due to ABCA3 deficiency. A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. Belongs to the ABC transporter superfamily. ABCA family. Protein type: Transporter; Membrane protein, multi-pass; Membrane protein, integral; Transporter, ABC family. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: extracellular space; membrane; plasma membrane; integral to membrane. Molecular Function: transporter activity; ATPase activity, coupled to transmembrane movement of substances; ATP binding. Biological Process: response to drug; metabolic process; transport; transmembrane transport. Disease: Surfactant Metabolism Dysfunction, Pulmonary, 3
size1 :
0.1 mg
price1 :
290 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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