PAK7 Antibody | MyBioSource MBS855963 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

PAK7 Antibody

catalog :

MBS855963

quantity :

0.1 mg

price :

215 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS855963

products type :

Antibody

products full name :

PAK7 Antibody

products short name :

PAK7

products name syn :

KIAA1264; p21-activated kinase 7; PAK 7; PAK-5; PAK-7; PAK5; PAK7

other names :

serine/threonine-protein kinase PAK 7; Serine/threonine-protein kinase PAK 7; serine/threonine-protein kinase PAK 7; PAK-5; PAK-7; protein kinase PAK5; p21-activated kinase 5; p21-activated kinase 7; p21CDKN1A-activated kinase 7; serine/threonine-protein kinase PAK7; p21 protein (Cdc42/Rac)-activated kinase 7; p21-activated kinase 5; PAK-5; p21-activated kinase 7; PAK-7

products gene name :

PAK7

other gene names :

PAK7; PAK7; PAK5; KIAA1264; PAK5; PAK-5; PAK-7

uniprot entry name :

PAK7_HUMAN

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

719

specificity :

PAK7 antibody detects endogenous levels of total PAK7 protein.

purity :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

form :

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

storage stability :

Store at -20 degree C for 1 year

tested application :

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

app notes :

WB: 1:500~1:1000, IHC: 1:50~1:100, ELISA: 1:40000

other info1 :

Reactivity Note: Human (Identities = 100%, Positives = 100%); Mouse (Identities = 100%, Positives = 100%); Rat (Identities = 100%, Positives = 100%)

other info2 :

Immunogen: The antiserum was produced against synthesized peptide derived from C-terminal of human PAK7. Pathway: Phosphatases/Kinases

products categories :

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

products references :

Pandey A., Oncogene 21:3939-3948(2002). Nagase T., DNA Res. 6:337-345(1999). Deloukas P., Nature 414:865-871(2001). -----------------------------------------------------------------------------------------------------------

ncbi gi num :

24308191

ncbi acc num :

NP_065074.1

ncbi gb acc num :

NM_020341.3

uniprot acc num :

Q9P286

ncbi mol weight :

80,745 Da

ncbi pathways :

Activation Of Rac Pathway (119530); Axon Guidance Pathway (83065); Axon Guidance Pathway (476); Axon Guidance Pathway (105688); Developmental Biology Pathway (477129); ErbB Signaling Pathway (83049); ErbB Signaling Pathway (458); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478)

ncbi summary :

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

uniprot summary :

PAK5: a protein kinase of the STE20 family. Predominantly expressed in brain. Capable of promoting neurite outgrowth, and thus may play a role in neurite development. Associated with microtubule networks and induces microtubule stabilization. Its subcellular localization is tightly regulated during cell cycle progression. Protein type: Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Kinase, protein; Protein kinase, STE; STE group; STE20 family; PAKB subfamily. Chromosomal Location of Human Ortholog: 20p12. Cellular Component: mitochondrion; cytoplasm; nucleus. Molecular Function: ATP binding; receptor signaling protein serine/threonine kinase activity. Biological Process: cell proliferation; cell migration; apoptosis; locomotory behavior; cytoskeleton organization and biogenesis; learning; mitotic cell cycle; cell growth; signal transduction; protein amino acid phosphorylation; memory

size1 :

0.1 mg

price1 :

215 USD

more info or order :

MyBioSource product webpage