product summary
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company name :
MyBioSource
product type :
antibody
product name :
DNA Polymerase zeta Antibody
catalog :
MBS855908
quantity :
0.1 mg
price :
215 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS855908
products type :
Antibody
products full name :
DNA Polymerase zeta Antibody
products short name :
DNA Polymerase zeta
products name syn :
DNA polymerase zeta catalytic subunit; DPOLZ; DPOZ; EC 2.7.7.7; POLZ; REV3L; SEZ4; Seizure-related protein 4; hREV3
other names :
DNA polymerase zeta catalytic subunit isoform b; DNA polymerase zeta catalytic subunit; DNA polymerase zeta catalytic subunit; Rev-3, yeast, homolog-like (polymerase, DNA, zeta); REV3-like, polymerase (DNA directed), zeta, catalytic subunit; Protein reversionless 3-like; REV3-like; hREV3
other gene names :
REV3L; REV3L; POLZ; REV3; POLZ; REV3; REV3-like; hREV3
uniprot entry name :
DPOLZ_HUMAN
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
3052
specificity :
DNA Polymerase zeta antibody detects endogenous levels of total DNA Polymerase zeta protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
1mg/ml
storage stability :
Store at -20 degree C for 1 year
tested application :
Immunohistochemistry (IHC), ELISA (EIA)
app notes :
IHC: 1:50~1:100, ELISA: 1:40000
other info1 :
Reactivity Note: Human (Identities = 100%, Positives = 100%); Mouse (Identities = 100%, Positives = 100%)
other info2 :
Immunogen: The antiserum was produced against synthesized peptide derived from internal of human DNA Polymerase zeta. Pathway: Transcription
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
Gibbs P.E.M., Proc. Natl. Acad. Sci. U.S.A. 95:6876-6880(1998). Lin W., Mutat. Res. 433:89-98(1999). Morelli C., Cytogenet. Cell Genet. 83:18-20(1998). ------------------------------------------------------------------------------------------------------------------------------------------
ncbi gi num :
556695361
ncbi acc num :
NP_001273360.1
ncbi gb acc num :
NM_001286431.1
uniprot acc num :
O60673
ncbi mol weight :
344,154 Da
ncbi pathways :
DNA Damage Bypass Pathway (105852); DNA Repair Pathway (105837); DNA Polymerase Zeta Complex Pathway (413480); DNA Polymerase Zeta Complex Pathway (468391); Fanconi Anemia Pathway (377262); Fanconi Anemia Pathway (377128); Metabolic Pathways (132956); Translesion Synthesis By DNA Polymerases Bypassing Lesion On DNA Template Pathway (105853); Translesion Synthesis By Pol Zeta Pathway (105856)
uniprot summary :
REV3: the DNA polymerase zeta catalytic subunit. Catalyzes the production of N diphosphate + {DNA}N from N deoxynucleoside triphosphate. Involved in translesion synthesis and required for the production of UV- and other DNA fork-blocking-induced mutations, as well as the majority of spontaneous mutations. Protein type: Transferase; EC 2.7.7.7; DNA replication. Chromosomal Location of Human Ortholog: 6q21. Cellular Component: nucleoplasm; zeta DNA polymerase complex; nucleolus; nucleus. Molecular Function: protein binding; DNA binding; metal ion binding; 4 iron, 4 sulfur cluster binding; nucleotide binding; DNA-directed DNA polymerase activity. Biological Process: error-prone postreplication DNA repair; DNA repair; DNA-dependent DNA replication
size1 :
0.1 mg
price1 :
215 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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