product summary
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company name :
MyBioSource
product type :
antibody
product name :
CD47 Antibody
catalog :
MBS855879
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, dog
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS855879
products type :
Antibody
products full name :
CD47 Antibody
products short name :
CD47
other names :
CD47 antigen; Leukocyte surface antigen CD47; CD47 antigen; Antigenic surface determinant protein OA3; Integrin-associated protein; IAP; Protein MER6; CD_antigen: CD47
products gene name :
CD47
other gene names :
CD47; CD47; MER6; IAP
uniprot entry name :
CD47_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human
sequence length :
303
form :
Lyophilized CD47 antibody purified by protein affinity column containing 1% BSA and 0.02% NaN3
concentration :
100ug/200ul
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
ELISA titer: 1:20,000-1:80,000. Western blot analysis: 1:1,000-1:2,000. Optimal dilutions/concentrations should be determined by the end user.
other info1 :
Source Note: Rabbit polyclonal CD47 (1) antibody was raised against a recombinate human CD47 protein 23-140aa (BC010016). Reactivity Note: Predicted: Mouse, Rat; Not yet tested in other species.
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
(1) Kaur,S., Kuznetsova,S.A., Pendrak,M.L. Heparan sulfate modification of the transmembrane receptor CD47 is necessary for inhibition of T cell receptor signaling by thrombospondin-1. J. Biol. Chem. 286 (17), 14991-15002 (2011)
ncbi gi num :
160333482
ncbi acc num :
BC010016
ncbi gb acc num :
NM_001080721.1
ncbi mol weight :
33,845 Da
ncbi pathways :
Cell Surface Interactions At The Vascular Wall Pathway (1016796); Cell-Cell Communication Pathway (1016221); ECM-receptor Interaction Pathway (84118); ECM-receptor Interaction Pathway (479); Extracellular Matrix Organization Pathway (1016234); Hemostasis Pathway (1016763); Integrin Cell Surface Interactions Pathway (1016250); Signal Regulatory Protein (SIRP) Family Interactions Pathway (1016231)
uniprot summary :
CD47: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 3q13.1-q13.2. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: protein binding. Biological Process: integrin-mediated signaling pathway; extracellular matrix organization and biogenesis; response to bacterium; positive regulation of phagocytosis; positive regulation of cell proliferation; positive regulation of cell-cell adhesion; opsonization; positive regulation of T cell activation; blood coagulation; cell adhesion; leukocyte migration; positive regulation of inflammatory response
size1 :
0.1 mg
price1 :
290 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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