catalog number :
MBS855876
products full name :
ABCB1 Antibody
products short name :
ABCB1
other names :
ABC transporter B family member 1; ABC transporter B family member 1; ABC transporter B family member 1; Multidrug resistance protein 1; P-glycoprotein 1; AtPgp1
products gene name :
ABCB1
other gene names :
ABCB1; ABCB1; ARABIDOPSIS THALIANA P GLYCOPROTEIN1; ATP binding cassette subfamily B1; ATPGP1; P-GLYCOPROTEIN 1; PGP1; T1J8.9; T1J8_9; MDR1; PGP1; ABC transporter ABCB.1; AtABCB1; AtPgp1
uniprot entry name :
AB1B_ARATH
reactivity :
Human, Mouse
form :
Lyophilized anti-ABCB1 antibody purified by peptide affinity column containing 1% BSA and 0.02% NaN3
concentration :
100ug/200ul
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA titer: 1:5,000-1:10,000. Western blot analysis: 1:500-1:1,000. Optimal dilutions/concentrations should be determined by the end user.
other info1 :
Source Note: Rabbit polyclonal ABCB1 (1) antibody was raised against a peptide from intermediate residues of human ABCB1 protein. Reactivity Note: Not yet tested in other species.
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
(1) Tournier,N., Valette,H., Peyronneau,M.A., et al. Transport of selected PET radiotracers by human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2): an in vitro screening. J. Nucl. Med. 52 (3), 415-423 (2011)
ncbi acc num :
NP_181228.1
ncbi gb acc num :
NM_129247.2
ncbi mol weight :
140,573 Da
ncbi pathways :
ABC Transporters Pathway (179811); ABC Transporters Pathway (436); ABC-family Proteins Mediated Transport Pathway (1007606); Abacavir Transmembrane Transport Pathway (1008019); Abacavir Transport And Metabolism Pathway (1008018); Bile Acid And Bile Salt Metabolism Pathway (1007868); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (1007841); Metabolism Pathway (1007804); Metabolism Of Lipids And Lipoproteins Pathway (1007835); PPARA Activates Gene Expression Pathway (1007858)
ncbi summary :
Belongs to the family of ATP-binding cassette (ABC) transporters. Also known as AtMDR1.Possibly regulates auxin-dependent responses by influencing basipetal auxin transport in the root. Exerts nonredundant, partially overlapping functions with the ABC transporter encoded by AT3G28860. PGP1 mediates cellular efflux of IAA and interacts with PIN genes that may confer an accelerated vectoral component to PGP-mediated transport. The non-polar localization of PGP1 at root and shoot apices, where IAA gradient-driven transport is impaired, may be required to confer directionality to auxin transport in those tissues.