catalog number :
MBS855778
products full name :
ACTN3 Antibody
products short name :
ACTN3
other names :
alpha-actinin-3 isoform 2; Alpha-actinin-3; alpha-actinin-3; F-actin cross-linking protein; alpha-actinin skeletal muscle; actinin, alpha 3; Alpha-actinin skeletal muscle isoform 3; F-actin cross-linking protein
products gene name :
ACTN3
other gene names :
ACTN3; ACTN3
uniprot entry name :
ACTN3_HUMAN
form :
Lyophilized ACTN3 antibody purified by protein A column containing 0.02% NaN3
concentration :
100ug/200ul
storage stability :
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at -20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
ELISA titer: 1:20,000-1:80,000. Western blot analysis: 1:500-1:1,000. Immunohistochemistry: 1:100-1:500. Optimal dilutions/concentrations should be determined by the end user.
other info1 :
Source Note: Rabbit polyclonal ACTN3 (1) antibody was raised against a recombinate human ACTN3 protein 325-608aa (BC099647). Reactivity Note: Predicted: Mouse, Rat; Not yet tested in other species.
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
ncbi acc num :
NP_001245300.1
ncbi gb acc num :
NM_001258371.1
ncbi mol weight :
103,241 Da
ncbi pathways :
Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Arrhythmogenic Right Ventricular Cardiomyopathy Pathway 672454!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 117293!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 116129!!Cell-Cell Communication Pathway 477132!!Focal Adhesion Pathway 83067!!Focal Adhesion Pathway 478
ncbi summary :
This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status. [provided by RefSeq, Feb 2014]