antibody

Ghsr Antibody

MBS855570

0.1 mg

290 USD

polyclonal

rabbit

nonconjugated

human, mouse, rat

western blot, immunohistochemistry

Antibody

Ghsr Antibody

Ghsr

Rattus norvegicus growth hormone secretagogue receptor (Ghsr), mRNA; Growth hormone secretagogue receptor type 1; growth hormone secretagogue receptor type 1; GHRP; GHS-R; ghrelin receptor; GH-releasing peptide receptor; growth hormone secretagogue receptor; GH-releasing peptide receptor; GHRP; Ghrelin receptor

Ghsr

Ghsr; Ghsr; GHS-R; GHRP

GHSR_RAT

Polyclonal

Rabbit

Human, Mouse, Rat

1350

Lyophilized Ghsr antibody purified by peptide affinity column containing 2% BSA and 0.02% NaN3

100ug/200ul

Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at -20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.

Western Blot (WB), Immunohistochemistry (IHC)

Peptide ELISA titer: 1:1,000-1:10,000. Western blot analysis: 1:200-1:1,000. Immunohistochemistry: 1:100-1:500. Optimal dilutions/concentrations should be determined by the end user.

Source Note: Rabbit polyclonal Ghsr (1) antibody was raised against a peptide from a peptide from near the N terminal residues of human Ghsr protein. Reactivity Note: Not yet tested in other species.

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

34419637

NP_114464.1

NM_032075

40,963 Da

Class A/1 (Rhodopsin-like Receptors) Pathway (1010164); G Alpha (q) Signalling Events Pathway (1010197); GPCR Downstream Signaling Pathway (1010193); GPCR Ligand Binding Pathway (1010163); GPCRs, Class A Rhodopsin-like Pathway (198500); Gastrin-CREB Signalling Pathway Via PKC And MAPK (1010213); Neuroactive Ligand-receptor Interaction Pathway (83445); Neuroactive Ligand-receptor Interaction Pathway (462); Peptide GPCRs Pathway (198538); Peptide Ligand-binding Receptors Pathway (1010165)

has G-protein coupled receptor binding activity to ligand ghrelin; plays a role in regulation of growth hormone release [RGD, Feb 2006]

GHSR: Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine). Defects in GHSR may be a cause of idiopathic short stature autosomal (ISSA). Short stature is defined by a subnormal rate of growth. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1. Cellular Component: neuron projection; cell surface; cell; integral to membrane; plasma membrane; lipid raft. Molecular Function: growth hormone secretagogue receptor activity; G-protein coupled receptor activity; protein binding; growth hormone receptor binding; hormone binding; peptide hormone binding; growth hormone-releasing hormone receptor activity. Biological Process: response to food; positive regulation of insulin-like growth factor receptor signaling pathway; hormone-mediated signaling; response to hormone stimulus; adult feeding behavior; negative regulation of interleukin-6 biosynthetic process; positive regulation of multicellular organism growth; decidualization; negative regulation of interleukin-1 beta production; negative regulation of insulin secretion; growth hormone secretion; G-protein coupled receptor protein signaling pathway; positive regulation of fatty acid metabolic process; regulation of synaptogenesis; cellular response to insulin stimulus; actin polymerization and/or depolymerization; negative regulation of inflammatory response; positive regulation of appetite; regulation of hindgut contraction; negative regulation of tumor necrosis factor biosynthetic process

0.1 mg

290 USD