antibody

IL13RA2 Antibody

MBS855456

0.1 mg

290 USD

polyclonal

rabbit

nonconjugated

western blot, ELISA, immunohistochemistry, enzyme immunoassay

Antibody

IL13RA2 Antibody

IL13RA2

interleukin-13 receptor subunit alpha-2; Interleukin-13 receptor subunit alpha-2; interleukin-13 receptor subunit alpha-2; IL-13RA2; IL-13R-alpha-2; IL-13R subunit alpha-2; cancer/testis antigen 19; IL-13 receptor subunit alpha-2; interleukin 13 binding protein; interleukin-13-binding protein; interleukin 13 receptor alpha 2 chain; interleukin 13 receptor, alpha 2; Interleukin-13-binding protein; CD_antigen: CD213a2

IL13RA2

IL13RA2; IL13RA2; CT19; IL-13R; IL13BP; CD213A2; IL13R; IL-13 receptor subunit alpha-2; IL-13R subunit alpha-2; IL-13R-alpha-2; IL-13RA2

I13R2_HUMAN

Polyclonal

Rabbit

Human

380

Lyophilized IL13RA2 antibody purified by protein A column containing 0.02% NaN3

0.5mg/ml

Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at -20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

ELISA titer: 1:20,000-1:80,000. Western blot analysis: 1:500-1:1,000. Immunohistochemistry: 1:100-1:500. Optimal dilutions/concentrations should be determined by the end use

Source Note: Rabbit polyclonal IL13RA2 (1) antibody was raised against a recombinate human IL13RA2 protein 72-349aa (BC020739). Reactivity Note: Predicted: Mouse, Rat; Not yet tested in other species.

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

10834992

NP_000631.1

NM_000640.2

44,176 Da

IL4-mediated Signaling Events Pathway (137933); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488)

The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. [provided by RefSeq, Jul 2008]

IL13RA2: a type I membrane protein that binds with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4). Lacks a cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. A member of the Cancer-Testis Antigen (CTA) superfamily. CTAs may play roles in embryonal development and tumor transformation or aspects of tumor progression. CTAs were once thought to be silenced in most normal adult tissues, with limited expression in fetal, placental, testis, and ovarian cells. These proteins are now known to be aberrantly expressed in various cancers and many are capable of eliciting humoral and cellular immune responses. The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. The box 1 motif is required for JAK interaction and/or activation. Often overexpressed in brain tumors. A potential vaccine targets for immunotherapy of glioma. Note: This description may include information from RefSeq and UniProtKB. Protein type: Receptor, cytokine; Cancer Testis Antigen (CTA); Membrane protein, integral. Chromosomal Location of Human Ortholog: Xq23. Cellular Component: extracellular space; integral to membrane. Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; signal transducer activity. Biological Process: cytokine and chemokine mediated signaling pathway; signal transduction

0.1 mg

290 USD