ATP5B Antibody | MyBioSource MBS855393 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

ATP5B Antibody

catalog :

MBS855393

quantity :

0.1 mg

price :

290 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS855393

products type :

Antibody

products full name :

ATP5B Antibody

products short name :

ATP5B

other names :

Homo sapiens ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (ATP5B), mRNA; ATP synthase subunit beta, mitochondrial; ATP synthase subunit beta, mitochondrial; epididymis secretory protein Li 271; mitochondrial ATP synthase beta subunit; mitochondrial ATP synthetase, beta subunit; ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide

products gene name :

ATP5B

other gene names :

ATP5B; ATP5B; ATPMB; ATPSB; HEL-S-271; ATPMB; ATPSB

uniprot entry name :

ATPB_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

1857

form :

Lyophilized anti-ATP5B antibody purified by peptide affinity column containing 1% BSA and 0.02% NaN3

concentration :

100ug/200ul

storage stability :

Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at -20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.

tested application :

Western Blot (WB), Immunohistochemistry (IHC)

app notes :

Peptide ELISA titer: 1:1,000-1:10,000. Western blot analysis: 1:500-1:1,000. Immunohistochemistry: 1:100-1:500. Optimal dilutions/concentrations should be determined by the end user.

other info1 :

Source Note: Rabbit polyclonal ATP5B (1) antibody was raised against a 16 amino acid peptide from near the intermediate of human ATP5B protein. Reactivity Note: Not yet tested in other species.

products categories :

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

ncbi gi num :

50345985

ncbi acc num :

NP_001677.2

ncbi gb acc num :

NM_001686

ncbi mol weight :

56,560 Da

ncbi pathways :

Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Electron Transport Chain Pathway (198860); F-type ATPase, Eukaryotes Pathway (522535); F-type ATPase, Eukaryotes Pathway (890450); Formation Of ATP By Chemiosmotic Coupling Pathway (105922); Huntington's Disease Pathway (83100); Huntington's Disease Pathway (512); Metabolic Pathways (132956); Metabolism Pathway (477135)

ncbi summary :

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the beta subunit of the catalytic core. [provided by RefSeq, Jul 2008]

uniprot summary :

ATP5B: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. Belongs to the ATPase alpha/beta chains family. Protein type: Energy Metabolism - oxidative phosphorylation; EC 3.6.3.14; Mitochondrial; Hydrolase. Chromosomal Location of Human Ortholog: 12q13.13. Cellular Component: mitochondrial proton-transporting ATP synthase, catalytic core; cell surface; membrane; mitochondrion; mitochondrial matrix; mitochondrial membrane; plasma membrane; nucleus; mitochondrial proton-transporting ATP synthase complex. Molecular Function: protein binding; MHC class I protein binding; transporter activity; ATPase activity; hydrogen ion transporting ATP synthase activity, rotational mechanism; transmembrane transporter activity; hydrogen ion transporting ATPase activity, rotational mechanism; ATP binding. Biological Process: mitochondrion organization and biogenesis; generation of precursor metabolites and energy; substrate-bound cell migration, cell release from substrate; organelle organization and biogenesis; osteoblast differentiation; cellular metabolic process; proton transport; ATP biosynthetic process; ATP hydrolysis coupled proton transport; regulation of intracellular pH; mitochondrial ATP synthesis coupled proton transport; angiogenesis; lipid metabolic process

size1 :

0.1 mg

price1 :

290 USD

more info or order :

MyBioSource product webpage