catalog number :
MBS855253
products full name :
HTR7 Antibody
products short name :
[HTR7]
products name syn :
[5-hydroxytryptamine receptor 7; 5-HT-7; Serotonin receptor 7; 5-HT-X; 5HT7; HTR7]
other names :
[5-hydroxytryptamine receptor 7 isoform a; 5-hydroxytryptamine receptor 7; 5-hydroxytryptamine receptor 7; 5-hydroxytryptamine receptor 7; 5-HT-X; Serotonin receptor 7]
products gene name :
[HTR7]
other gene names :
[HTR7; HTR7; 5-HT7; 5-HT-7; 5-HT7]
reactivity :
Human (Identities = 100%, Positives = 100%). Mouse (Identities = 93%, Positives = 93%). Rat (Identities = 93%, Positives = 93%)
specificity :
HTR7 antibody detects endogenous levels of total HTR7 protein.
purity :
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at-20 degree C for 1 year.
tested application :
Immunofluorescence (IF), ELISA (EIA)
app notes :
IF: 1:100~1:500, ELISA: 1:5000
image1 heading :
Immunofluorescence (IF)
other info1 :
Immunogen: The antiserum was produced against synthesized peptide derived from internal of human HTR7.
products references :
Heidmann D.E.A., J. Neurochem. 68:1372-1381(1997). Bard J.A., J. Biol. Chem. 268:23422-23426(1993). King M.M., Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
ncbi acc num :
NP_000863.1
ncbi gb acc num :
NM_000872.4
ncbi mol weight :
47,984 Da
ncbi pathways :
Amine Ligand-binding Receptors Pathway (106363); Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class A Rhodopsin-like Pathway (198886); GPCRs, Other Pathway (198765); Monoamine GPCRs Pathway (198861)
ncbi summary :
The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq, Jul 2008]
uniprot summary :
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.