catalog number :
MBS855176
products full name :
IL17 Antibody
products short name :
IL17
other names :
interleukin-17A; Interleukin-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8
products gene name :
IL17
other gene names :
IL17A; IL17A; IL17; CTLA8; IL-17; IL-17A; CTLA8; IL17; IL-17; IL-17A; CTLA-8
uniprot entry name :
IL17_HUMAN
specificity :
Anti-IL17 recognizes recombinant IL17.
form :
Each vial contains 100 ug IgG in 100 ul of citrate-tris-HCl buffer pH7.0 with 0.02% Proclin 300.
storage stability :
The antibody may be stored at -20 degree C for one year in its original formulation. Additionally, antibody may be stored at 2 degree C to 8 degree C for up to 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles of the diluted antibody.
tested application :
ELISA (EIA)
other info1 :
Source Note: Purified mouse monoclonal antibody generated using E Coli expressed recombinant protein IL17 as immunogen.
other info2 :
Immunogen: Recombinant protein corresponding to fragment (aa/25-155) IL17.
products categories :
Plant antibody
ncbi acc num :
NP_002181.1
ncbi gb acc num :
NM_002190.2
ncbi mol weight :
17,504 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!IL17 Signaling Pathway 920968!!IL23-mediated Signaling Events Pathway 138000!!IL27-mediated Signaling Events Pathway 137929!!Inflammatory Bowel Disease (IBD) Pathway 842771!!Inflammatory Bowel Disease (IBD) Pathway 842797!!Rheumatoid Arthritis Pathway 200309!!Rheumatoid Arthritis Pathway 200269!!TCR Signaling Pathway 198862
ncbi summary :
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]