catalog number :
MBS855131
products full name :
ETS1 (Phospho-Thr38) Antibody
products short name :
ETS1
products name syn :
C-ets-1 protein; ETS-1; ETS1; p54
other names :
protein C-ets-1 isoform 1; Protein C-ets-1; protein C-ets-1; v-ets avian erythroblastosis virus E2 oncogene homolog 1; Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1; v-ets avian erythroblastosis virus E26 oncogene homolog 1; p54
products gene name :
ETS1
other gene names :
ETS1; ETS1; p54; ETS-1; EWSR2; EWSR2
uniprot entry name :
ETS1_HUMAN
reactivity :
Human, Mouse
specificity :
ETS1 (Phospho-Thr38) antibody detects endogenous levels of ETS1 only when phosphorylated at threonine 38.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20 degree C for 1 year
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
app notes :
WB: 1:500~1:1000, IHC: 1:50~1:100, IF: 1:100~1:500, ELISA: 1:10000
other info2 :
Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human ETS1 around the phosphorylation site of threonine 38 (L-L-TP-P-S). All Sites: Human: Thr38; Mouse: Thr38. Pathway: Phospho-specific
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
Tsukasa Higuchi, Mol. Cell. Biol., May 2007; 27: 3353 - 3366. NK Bhat, PNAS, May 1990; 87: 3723. H Suzuki, PNAS, May 1995; 92: 4442. V Fafeur, Cell Growth Differ., Jun 1997; 8: 655.
ncbi acc num :
NP_001137292.1
ncbi gb acc num :
NM_001143820.1
ncbi mol weight :
30,860 Da
ncbi pathways :
Angiopoietin Receptor Tie2-mediated Signaling Pathway 137917!!BCR Signaling Pathway 138058!!C-MYB Transcription Factor Network Pathway 138073!!Cellular Senescence Pathway 905991!!Cellular Responses To Stress Pathway 645258!!Dorso-ventral Axis Formation Pathway 114227!!Dorso-ventral Axis Formation Pathway 472!!HIF-1-alpha Transcription Factor Network Pathway 138045!!HIF-2-alpha Transcription Factor Network Pathway 137956!!HTLV-I Infection Pathway 373901
ncbi summary :
This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]