product summary
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company name :
MyBioSource
product type :
antibody
product name :
MRC1 Antibody
catalog :
MBS855077
quantity :
0.1 mg
price :
215 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS855077
products type :
Antibody
products full name :
MRC1 Antibody
products short name :
MRC1
products name syn :
Macrophage mannose receptor 1; MMR; CD206 antigen
other names :
macrophage mannose receptor 1; Macrophage mannose receptor 1; macrophage mannose receptor 1; mannose receptor, C type 1-like 1; C-type lectin domain family 13 member D; macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1; CD_antigen: CD206
products gene name :
MRC1
other gene names :
MRC1; MRC1; MMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1; CLEC13D; CLEC13DL; MRC1L1; MMR
uniprot entry name :
MRC1_HUMAN
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
1456
specificity :
MRC1 antibody detects endogenous levels of total MRC1 protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
1mg/ml
storage stability :
Store at -20 degree C for 1 year
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
WB: 1:500~1:1000, ELISA: 1:20000
other info1 :
Reactivity Note: Human (Identities = 100%, Positives = 100%); Mouse (Identities = 100%, Positives = 100%); Rat (Identities = 100%, Positives = 100%). Swiss-Prot No.: P22897
other info2 :
Immunogen: The antiserum was produced against synthesized peptide CLYAKGKHEKKTWFE derived from internal of human MRC1. Pathway: Lymphocyte Signaling
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
Taylor M.E., J. Biol. Chem. 265:12156-12162(1990). Ezekowitz R.A., J. Exp. Med. 172:1785-1794(1990). Kim S.J., Genomics 14:721-727(1992).
ncbi gi num :
4505245
ncbi acc num :
NP_002429.1
ncbi gb acc num :
NM_002438.3
uniprot acc num :
P22897
ncbi mol weight :
56,554 Da
ncbi pathways :
Adaptive Immune System Pathway (366160); Antigen Processing-Cross Presentation Pathway (477122); Class I MHC Mediated Antigen Processing Presentation Pathway (366161); Cross-presentation Of Soluble Exogenous Antigens (endosomes) Pathway (477126); Immune System Pathway (106386); Phagosome Pathway (153910); Phagosome Pathway (153859); Tuberculosis Pathway (213780); Tuberculosis Pathway (213743)
ncbi summary :
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Apr 2011]
uniprot summary :
MRC1: Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 10p12.33. Cellular Component: cell surface; integral to plasma membrane; plasma membrane; endosome membrane. Molecular Function: mannose binding; protein binding; transmembrane receptor activity; receptor activity. Biological Process: receptor-mediated endocytosis; signal transduction
size1 :
0.1 mg
price1 :
215 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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