product summary
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company name :
MyBioSource
product type :
antibody
product name :
AHRR Antibody
catalog :
MBS854940
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS854940
products type :
Antibody
products full name :
AHRR Antibody
products short name :
AHRR
other names :
aryl hydrocarbon receptor repressor isoform 2; Aryl hydrocarbon receptor repressor; aryl hydrocarbon receptor repressor; ahR repressor; dioxin receptor repressor; aryl hydrocarbon hydroxylase regulator; class E basic helix-loop-helix protein 77; aryl-hydrocarbon receptor repressor; Class E basic helix-loop-helix protein 77; bHLHe77
products gene name :
AHRR
other gene names :
AHRR; AHRR; AHH; AHHR; bHLHe77; BHLHE77; KIAA1234; AhR repressor; AhRR; bHLHe77
uniprot entry name :
AHRR_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Rat, Mouse
sequence length :
701
form :
Lyophilized anti-AHRR antibody purified by peptide affinity column containing 1% BSA and 0.02% NaN3
concentration :
100ug/200ul
storage stability :
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at -20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
tested application :
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
app notes :
Peptide ELISA titer: 1:10,000-1:40,000. Western blot analysis: 1:1,000-1:2,000. Immunohistochemistry: 1:100-1:500. Optimal dilutions/concentrations should be determined by the end user.
other info1 :
Source Note: Rabbit polyclonal AHRR (1) antibody was raised against a peptide from N terminal residues of human AHRR protein. Reactivity Note: Not yet tested in other species.
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
ncbi gi num :
334848123
ncbi acc num :
NP_001229341.1
ncbi gb acc num :
NM_001242412.1
ncbi mol weight :
77,821 Da
ncbi pathways :
AhR Pathway (755436)
ncbi summary :
The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]
uniprot summary :
AHRR: Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Transcription factor. Chromosomal Location of Human Ortholog: 5p15.3. Cellular Component: cytoplasm. Molecular Function: protein dimerization activity; signal transducer activity; DNA binding. Biological Process: positive regulation of protein sumoylation; response to xenobiotic stimulus; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; signal transduction
size1 :
0.1 mg
price1 :
290 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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