catalog number :
MBS854796
products full name :
MRPL40 Antibody
products short name :
MRPL40
products name syn :
39S ribosomal protein L40; mitochondrial; L40mt; mitochondrial ribosomal protein L40; MRP-40; MRP-L22; NLVCF; nuclear localization signal-containing protein deleted in velocardiofacial syndrome; RM40; up-regulated in metastasis; URIM
other names :
39S ribosomal protein L40, mitochondrial; 39S ribosomal protein L40, mitochondrial; 39S ribosomal protein L40, mitochondrial; L40mt; MRP-L40; up-regulated in metastasis; nuclear localization signal deleted in velocardiofacial syndrome; nuclear localization signal containing protein deleted in velocardiofacial syndrome; nuclear localization signal-containing protein deleted in velocardiofacial syndrome; mitochondrial ribosomal protein L40; Nuclear localization signal-containing protein deleted in velocardiofacial syndrome; Up-regulated in metastasis
products gene name :
MRPL40
other gene names :
MRPL40; MRPL40; URIM; NLVCF; MRPL22; MRP-L22; NLVCF; URIM; L40mt; MRP-L40
uniprot entry name :
RM40_HUMAN
specificity :
MRPL40 antibody detects endogenous levels of total MRPL40 protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20 degree C for 1 year
tested application :
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
app notes :
WB: 1:500~1:1000, IHC: 1:50~1:100, ELISA: 1:40000
other info1 :
Reactivity Note: Human (Identities = 100%, Positives = 100%)
other info2 :
Immunogen: The antiserum was produced against synthesized peptide derived from internal of human MRPL40. Pathway: Intermediates
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004). The MGC Project Team; Genome Res. 14:2121-2127(2004). Hildebrandt T., Anticancer Res. 19:525-530(1999). ------------------------------------------------------------------------------------------------------------------------------------------
ncbi acc num :
NP_003767.2
ncbi gb acc num :
NM_003776.2
ncbi mol weight :
24,490 Da
ncbi summary :
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome. [provided by RefSeq, Jul 2008]
uniprot summary :
MRPL40: . Protein type: Mitochondrial. Chromosomal Location of Human Ortholog: 22q11.2. Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial ribosome; nucleolus; nucleus. Biological Process: anatomical structure morphogenesis; mitochondrial translation; organelle organization and biogenesis