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WASF2 Antibody

MBS854732

0.1 mg

280 USD

Antibody

WASF2 Antibody

[WASF2]

[Wiskott-Aldrich syndrome protein family member 2; WASP family protein member 2; Protein WAVE-2; Verprolin homology domain-containing protein 2; WASF2]

[wiskott-Aldrich syndrome protein family member 2 isoform 2; Wiskott-Aldrich syndrome protein family member 2; wiskott-Aldrich syndrome protein family member 2; WAS protein family member 2; Protein WAVE-2; Verprolin homology domain-containing protein 2]

[WASF2]

[WASF2; WASF2; IMD2; SCAR2; WASF4; WAVE2; dJ393P12.2; WASP family protein member 2]

Human, Mouse, Rat

281

WASF2 antibody detects endogenous levels of total WASF2 protein.

Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Store at-20 degree C for 1 year.

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

WB: 1:500~1:1000. IHC: 1:50~1:100. ELISA: 1:1000

Testing Data

Immunohistochemistry (IHC)

Immunogen: The antiserum was produced against synthesized peptide derived from internal of human WASF2.

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells

Suetsugu S., Biochem. Biophys. Res. Commun. 260:296-302(1999). Gregory S.G., Nature 441:315-321(2006). Miki H., Nature 408:732-735(2000).

319655728

NP_001188333.1

NM_001201404.2

Q9Y6W5

31,979 Da

Adherens Junction Pathway (83070); Adherens Junction Pathway (481); Bacterial Invasion Of Epithelial Cells Pathway (149807); Bacterial Invasion Of Epithelial Cells Pathway (148661); E-cadherin Signaling In The Nascent Adherens Junction Pathway (138005); ErbB1 Downstream Signaling Pathway (138057); Fc Gamma R-mediated Phagocytosis Pathway (114228); Fc Gamma R-mediated Phagocytosis Pathway (106590); Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway (771577); Immune System Pathway (106386)

This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.

0.1 mg

280 USD