CKMT2 Antibody | MyBioSource MBS854621 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

CKMT2 Antibody

catalog :

MBS854621

quantity :

0.1 mg

price :

215 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunocytochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS854621

products type :

Antibody

products full name :

CKMT2 Antibody

products short name :

CKMT2

products name syn :

Creatine kinase; sarcomeric mitochondrial [Precursor]; EC 2.7.3.2; S-MtCK; Mib-CK; Basic-type mitochondrial creatine kinase; CKMT2

other names :

creatine kinase S-type, mitochondrial; Creatine kinase S-type, mitochondrial; creatine kinase S-type, mitochondrial; S-MtCK; mib-CK; basic-type mitochondrial creatine kinase; sarcomeric mitochondrial creatine kinase; creatine kinase, mitochondrial 2 (sarcomeric); Basic-type mitochondrial creatine kinase; Mib-CK; Sarcomeric mitochondrial creatine kinase; S-MtCK

products gene name :

CKMT2

other gene names :

CKMT2; CKMT2; SMTCK; Mib-CK; S-MtCK

uniprot entry name :

KCRS_HUMAN

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

419

specificity :

CKMT2 antibody detects endogenous levels of total CKMT2 protein.

purity :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

form :

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

concentration :

1mg/ml

storage stability :

Store at -20 degree C for 1 year

tested application :

Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)

app notes :

WB: 1:500~1:1000, IF: 1:100~1:500, ELISA: 1:40000

other info2 :

Immunogen: The antiserum was produced against synthesized peptide derived from internal of human CKMT2. Pathway: Phosphatases/Kinases

products categories :

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

products references :

Haas R.C., J. Biol. Chem. 265:6921-6927(1990). The MGC Project Team, Genome Res. 14:2121-2127(2004). Haas R.C., J. Biol. Chem. 264:2890-2897(1989). ------------------------------------------------------------------------------------------------------------------------------------------

ncbi gi num :

153251984

ncbi acc num :

NP_001093205.1

ncbi gb acc num :

NM_001099735.1

uniprot acc num :

P17540

ncbi mol weight :

47,504 Da

ncbi pathways :

Arginine And Proline Metabolism Pathway (82957); Arginine And Proline Metabolism Pathway (323); Creatine Metabolism Pathway (106192); Creatine Pathway (413359); Creatine Pathway (468234); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Amino Acids And Derivatives Pathway (106169); Creatine-phosphate Biosynthesis Pathway (545319); Creatine-phosphate Biosynthesis Pathway (138632)

ncbi summary :

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

CKMT2: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family. Protein type: EC 2.7.3.2; Mitochondrial; Amino Acid Metabolism - arginine and proline; Kinase, other. Chromosomal Location of Human Ortholog: 5q13.3. Cellular Component: mitochondrion; mitochondrial inner membrane. Molecular Function: creatine kinase activity; ATP binding. Biological Process: muscle contraction; creatine metabolic process; phosphorylation

size1 :

0.1 mg

price1 :

215 USD

more info or order :

MyBioSource product webpage