catalog number :
MBS854284
products full name :
TnI Antibody
products short name :
TnI
other names :
unnamed protein product; Troponin I, cardiac muscle; troponin I, cardiac muscle; cardiomyopathy, dilated 2A (autosomal recessive); troponin I type 3 (cardiac); Cardiac troponin I
other gene names :
TNNI3; TNNI3; CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF; TNNC1
uniprot entry name :
TNNI3_HUMAN
specificity :
Anti-TnI recognizes mouse heart tissue protein TnI.
form :
Each vial contains 100 ug IgG in 100 ul of citrate-tris-HCl buffer pH7.0 with 0.02% Proclin 300.
storage stability :
The antibody may be stored at -20 degree C for one year in its original formulation. Additionally, antibody may be stored at 2 degree C to 8 degree C for up to 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles of the diluted antibody.
tested application :
ELISA (EIA), Western Blot (WB-Re)
app notes :
Anti-TnI can be used in ELISA and WB-Ce. Can be used as a capture antibody in sandwich ELISA applications for human TnI detection in combination with a monoclonal detection antibody.
other info1 :
Source Note: Purified mouse monoclonal antibody generated using E Coli expressed recombinant protein TnI as immunogen.
other info2 :
Immunogen: Recombinant protein corresponding to full length TnI.
products categories :
Plant antibody
ncbi mol weight :
24,008 Da
ncbi pathways :
Adrenergic Signaling In Cardiomyocytes Pathway 908257!!Adrenergic Signaling In Cardiomyocytes Pathway 909696!!Cardiac Progenitor Differentiation Pathway 712094!!Cardiac Muscle Contraction Pathway 93344!!Cardiac Muscle Contraction Pathway 93992!!Dilated Cardiomyopathy Pathway 121494!!Dilated Cardiomyopathy Pathway 121285!!Hypertrophic Cardiomyopathy (HCM) Pathway 114229!!Hypertrophic Cardiomyopathy (HCM) Pathway 106591!!Muscle Contraction Pathway 106261
ncbi summary :
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]