catalog number : 
MBS854142
products full name : 
CREB1 Antibody
products short name : 
CREB1
other names : 
Homo sapiens cAMP responsive element binding protein 1 (CREB1), transcript variant A, mRNA; Cyclic AMP-responsive element-binding protein 1; cyclic AMP-responsive element-binding protein 1; CREB-1; transactivator protein; active transcription factor CREB; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; cAMP responsive element binding protein 1
products gene name : 
CREB1
other gene names : 
CREB1; CREB1; CREB; CREB-1; cAMP-responsive element-binding protein 1
uniprot entry name : 
CREB1_HUMAN
reactivity : 
Human, Mouse, Rat
form : 
Lyophilized anti-CREB1 antibody purified by protein A column containing 0.02% NaN3
concentration : 
100ul/200ul
tested application : 
Western Blot (WB)
app notes : 
Peptide ELISA titer: 1:40,000-1:80,000. Western blot analysis: 1:200-1,000. Optimal dilutions/concentrations should be determined by the end user.
other info1 : 
Source Note: Rabbit polyclonal CREB1 (1) antibody was raised against a peptide near intermediate residues of human CREB1 protein.  Reactivity Note: Not yet tested in other species.
products categories : 
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references : 
(1) James,M.A., Lu,Y., Liu,Y., et al.RGS17, an overexpressed gene in human lung and prostate cancer, induces tumor cell proliferation through the cyclic AMP-PKA-CREB pathway.Cancer Res. 69 (5), 2108-2116 (2009)
ncbi acc num : 
NP_004370.1
ncbi gb acc num : 
NM_004379
ncbi mol weight : 
25,445 Da
ncbi pathways : 
AKT Phosphorylates Targets In The Nucleus Pathway  106476!!AMPK Signaling Pathway  989139!!AMPK Signaling Pathway  992181!!ATF-2 Transcription Factor Network Pathway  138006!!ATM Signaling Pathway  920969!!Activated TLR4 Signalling Pathway  106400!!Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway  161033!!Adaptive Immune System Pathway  366160!!Adipogenesis Pathway  198832!!Adrenergic Signaling In Cardiomyocytes Pathway  908257
ncbi summary : 
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]