catalog number :
MBS854065
products full name :
neurogenin 1 Antibody
products short name :
neurogenin 1
other names :
neurogenin-1; Neurogenin-1; neurogenin-1; NGN-1; neurogenic differentiation 3; neurogenic differentiation factor 3; class A basic helix-loop-helix protein 6; neurogenic basic-helix-loop-helix protein; neurogenin 1; Class A basic helix-loop-helix protein 6; bHLHa6; Neurogenic basic-helix-loop-helix protein; Neurogenic differentiation factor 3; NeuroD3
other gene names :
NEUROG1; NEUROG1; AKA; ngn1; Math4C; bHLHa6; NEUROD3; BHLHA6; NEUROD3; NGN; NGN1; NGN-1; bHLHa6; NeuroD3
uniprot entry name :
NGN1_HUMAN
reactivity :
Human, Mouse, Rat
form :
Lyophilized anti-neurogeni -n 1 antibody purified by peptide affinity column containing 0.5% BSA and 0.02% NaN3
concentration :
100ug/200ul
storage stability :
Stable for atleast 1 year when stored at -20 degree C after reconstitution. Avoid repeated freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Peptide ELISA titer: 1:80,000. Western blot analysis: 1:200-1:500. Optimal dilutions/concentrations should be determined by the end user.
other info1 :
Source Note: Rabbit polyclonal neurogenin 1 (1) antibody was raised against a 16 amino acid peptide from near the N terminal residues of human neurogenin 1 protein. Reactivity Note: Not yet tested in other species.
other info2 :
Pathway: neurogenin 1 . Dilution instruction: Reconstituted in 200ul sterile H2O.
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
(1)McCormick,M.B., Tamimi,R.M., Snider,L., et,al. NeuroD2 and neuroD3: distinct expression patterns and transcriptional activation potentials within the neuroD gene family Mol. Cell. Biol. 1996;16 (10):5792-5800.
ncbi gb acc num :
NM_006161.2
ncbi mol weight :
25,718 Da
ncbi pathways :
Neural Crest Differentiation Pathway (672460); Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway (169352); Signaling Pathways Regulating Pluripotency Of Stem Cells (1026136); Signaling Pathways Regulating Pluripotency Of Stem Cells (1033502)
uniprot summary :
neurogenin 1: Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5 -CANNTG-3 ). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis. Protein type: Cell development/differentiation; DNA-binding; Transcription factor. Chromosomal Location of Human Ortholog: 5q23-q31. Cellular Component: perikaryon; nucleus. Molecular Function: protein dimerization activity; DNA binding; chromatin binding; transcription factor activity. Biological Process: neuron differentiation; regulation of transcription from RNA polymerase II promoter; nervous system development; inner ear morphogenesis; cell fate commitment; transcription, DNA-dependent; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of neuron differentiation; positive regulation of exit from mitosis