catalog number :
MBS853867
products full name :
IL4I1 Antibody
products short name :
IL4I1
products name syn :
Fig-1 protein; FIG1; hFIG1; IL4-induced protein 1; IL4I1; interleukin 4 induced 1; interleukin 4 induced protein 1; interleukin four induced 1; Interleukin-4-induced protein 1; L-amino-acid oxidase; LAAO; LAO; OXLA; Protein Fig-1
other names :
L-amino-acid oxidase isoform 2; L-amino-acid oxidase; L-amino-acid oxidase; Fig-1 protein; IL4-induced protein 1; interleukin four induced 1; interleukin 4 induced 1; Interleukin-4-induced protein 1; IL4-induced protein 1; Protein Fig-1; hFIG1
products gene name :
IL4I1
other gene names :
IL4I1; IL4I1; LAO; FIG1; LAAO; FIG1; LAAO; LAO; IL4-induced protein 1; hFIG1
uniprot entry name :
OXLA_HUMAN
specificity :
IL4I1 antibody detects endogenous levels of total IL4I1 protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20 degree C for 1 year
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
WB: 1:500~1:3000, ELISA: 1:40000
other info2 :
Immunogen: The antiserum was produced against synthesized peptide derived from N-terminal of human IL4I1. Pathway: Intermediates
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
Chavan S.S., Biochim. Biophys. Acta 1576:70-80(2002). Wiemann S., BMC Biol. 3:16-16(2005). Clark H.F., Genome Res. 13:2265-2270(2003). ------------------------------------------------------------------------------------------------------------------------------------------
ncbi acc num :
NP_001244946.1
ncbi gb acc num :
NM_001258017.1
ncbi mol weight :
65,328 Da
ncbi pathways :
Abnormal Metabolism In Phenylketonuria Pathway (645287); Alanine, Aspartate And Glutamate Metabolism Pathway (101142); Alanine, Aspartate And Glutamate Metabolism Pathway (100063); Cysteine And Methionine Metabolism Pathway (104488); Cysteine And Methionine Metabolism Pathway (103421); Disease Pathway (530764); Metabolic Pathways (132956); Phenylalanine Metabolism Pathway (82960); Phenylalanine Metabolism Pathway (327); Phenylalanine, Tyrosine And Tryptophan Biosynthesis Pathway (82965)
ncbi summary :
This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
uniprot summary :
IL4I1: Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation. Belongs to the flavin monoamine oxidase family. FIG1 subfamily. 2 isoforms of the human protein are produced by alternative promoter. Protein type: Amino Acid Metabolism - tryptophan; Secreted; Amino Acid Metabolism - alanine, aspartate and glutamate; Amino Acid Metabolism - phenylalanine, tyrosine and tryptophan biosynthesis; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Amino Acid Metabolism - cysteine and methionine; Oxidoreductase; EC 1.4.3.2; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 19q13.3-q13.4. Cellular Component: lysosome; extracellular region. Molecular Function: L-amino-acid oxidase activity