product summary
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company name :
MyBioSource
product type :
antibody
product name :
CLK1 Antibody
catalog :
MBS853849
quantity :
0.1 mg
price :
215 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry, enzyme immunoassay
more info or order :
product information
catalog number :
MBS853849
products type :
Antibody
products full name :
CLK1 Antibody
products short name :
CLK1
products name syn :
CDC like kinase 1; CLK; CLK1; Dual specificity protein kinase CLK1; EC 2.7.1.112; EC 2.7.12.1
other names :
dual specificity protein kinase CLK1 isoform 2; Dual specificity protein kinase CLK1; dual specificity protein kinase CLK1; CDC28/CDC2-like kinase; protein tyrosine kinase STY; CDC-like kinase 1; CDC-like kinase 1
products gene name :
CLK1
other gene names :
CLK1; CLK1; CLK; STY; CLK/STY; CLK
uniprot entry name :
CLK1_HUMAN
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
526
specificity :
CLK1 antibody detects endogenous levels of total CLK1 protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20 degree C for 1 year
tested application :
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
app notes :
WB: 1:500~1:1000, IF: 1:100~1:500, ELISA: 1:1000
other info2 :
Immunogen: The antiserum was produced against synthesized peptide derived from internal of human CLK1. Pathway: Phosphatases/Kinases
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
Johnson K.W., J. Biol. Chem. 266:3402-3407(1991). Hanes J.J., J. Mol. Biol. 244:665-672(1994). Olsen J.V., Cell 127:635-648(2006). -----------------------------------------------------------------------------------------------------------------------------------------
ncbi gi num :
241666392
ncbi acc num :
NP_001155879.1
ncbi gb acc num :
NM_001162407.1
uniprot acc num :
P49759
ncbi mol weight :
61,757 Da
ncbi pathways :
Legionellosis Pathway (469200); Legionellosis Pathway (469186); MRNA Processing Pathway (198843)
ncbi summary :
This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
uniprot summary :
CLK1: a CMGC kinase of the CLK family. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May play a role in regulating RNA splicing. Protein type: Kinase, protein; Protein kinase, CMGC; EC 2.7.12.1; Protein kinase, dual-specificity (non-receptor); CMGC group; CLK family. Chromosomal Location of Human Ortholog: 2q33. Cellular Component: cytoplasm; nucleus. Molecular Function: protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; non-membrane spanning protein tyrosine kinase activity; ATP binding. Biological Process: cell proliferation; peptidyl-serine phosphorylation; peptidyl-tyrosine phosphorylation; regulation of RNA splicing; protein amino acid autophosphorylation; peptidyl-threonine phosphorylation
size1 :
0.1 mg
price1 :
215 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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