catalog number :
MBS853662
products full name :
ACN9 Antibody
products short name :
[ACN9]
other names :
[succinate dehydrogenase assembly factor 3, mitochondrial; Succinate dehydrogenase assembly factor 3, mitochondrial; succinate dehydrogenase assembly factor 3, mitochondrial; succinate dehydrogenase complex assembly factor 3]
products gene name :
[ACN9]
other gene names :
[SDHAF3; SDHAF3; ACN9; DC11; Sdh7; LYRM10; SDHAF3]
reactivity :
Human - Not yet tested in other species.
form :
Lyophilized anti-ACN9 antibody purified by peptide affinity column containing 0.5% BSA and 0.02% NaN3
storage stability :
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Peptide ELISA: 1:5,000-1:10,000. WB: 1:1,000-1:2,000. IHC: 1:100-500 . Optimal dilutions/concentrations should be determined by the end user.
image1 heading :
Testing Data
image2 heading :
Testing Data
products categories :
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
products description :
Rabbit polyclonal ACN9 (1) antibody was raised against a peptide from intermediate residues of human ACN9 protein.
products references :
(1) Dick, D.M., Aliev, F., Wang, J.C., et al. A Systematic single nucleotide polymorphism screen to fine-map alcohol dependence genes on chromosome 7 identifies association with a novel susceptibility gene ACN9. Biol. Psychiatry 63 (11), 1047-1053 (2008).
ncbi acc num :
NP_064571.1
ncbi gb acc num :
NM_020186.2
uniprot summary :
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.