catalog number :
MBS853640
products full name :
BMP3 Antibody
products short name :
BMP3
products name syn :
Bone morphogenetic protein 3; BMP-3; Osteogenin; BMP-3A; Bone morphogenetic protein 3A
other names :
bone morphogenetic protein 3 preproprotein; Bone morphogenetic protein 3; bone morphogenetic protein 3; BMP-3; osteogenin; bone morphogenetic protein-3; bone morphogenetic protein 3A; bone morphogenetic protein 3 (osteogenic); bone morphogenetic protein 3; Bone morphogenetic protein 3A; BMP-3A; Osteogenin
products gene name :
BMP3
other gene names :
BMP3; BMP3; BMP-3A; BMP3A; BMP-3; BMP-3A
uniprot entry name :
BMP3_HUMAN
specificity :
BMP3 antibody detects endogenous levels of total BMP3 protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20 degree C for 1 year
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
WB: 1:500~1:1000, ELISA: 1:5000
other info1 :
Reactivity Note: Human (Identities = 100%, Positives = 100%)
other info2 :
Immunogen: The antiserum was produced against synthesized peptide derived from internal of human BMP3. Pathway: Growth Factors
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
Wozney J.M., Science 242:1528-1534(1988). Hillier L.W., Nature 434:724-731(2005). Daluiski A., Nat. Genet. 27:84-88(2001). ----------------------------------------------------------------------------------------------------------------------------------
ncbi acc num :
NP_001192.2
ncbi gb acc num :
NM_001201.2
ncbi mol weight :
53,372 Da
ncbi pathways :
Adipogenesis Pathway (198832)
ncbi summary :
BMP3 belongs to the transforming growth factor-beta (TGFB) superfamily. Bone morphogenic protein, also known as osteogenin, induces bone formation. [provided by RefSeq, Jul 2008]
uniprot summary :
BMP3: Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. Belongs to the TGF-beta family. Protein type: Secreted; Cytokine; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 4q21. Cellular Component: extracellular space. Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding; receptor binding. Biological Process: regulation of apoptosis; ossification; cell-cell signaling; cartilage development; regulation of MAPKKK cascade; positive regulation of transcription from RNA polymerase II promoter; cell development; skeletal development; growth