catalog number :
MBS853636
products full name :
ALP Antibody
products short name :
[ALP]
other names :
[PDZ and LIM domain protein 3 isoform a; PDZ and LIM domain protein 3; PDZ and LIM domain protein 3; PDZ and LIM domain 3; Actinin-associated LIM protein; Alpha-actinin-2-associated LIM protein]
products gene name :
[ALP]
other gene names :
[PDLIM3; PDLIM3; ALP; ALP]
reactivity :
Human, Rat, Mouse. Not yet tested in other species.
form :
Lyophilized rabbit anti-ALP serum containin 0.02% NaN 3
storage stability :
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at -20°C after reconstitution. Avoid repeated freeze/defrost cycles.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: 1:10,000-1:40,000. WB: 1:500-1:1,000. Optimal dilutions/concentrations should be determined by the end user.
image1 heading :
Testing Data
other info1 :
Host Note: Rabbit polyclonal ALP (1) antibody was raised against a 14 amino acid peptide corresponding to C terminal residues of human ALP.
products categories :
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
products references :
(1)Pietu, G., Alibert, O., Guichard, V., et, al Novel gene transcripts preferentially expressed in human muscles revealed by quantitative hybridization of a high density cDNA array. Genome Res. 1996; 6:492-503.
ncbi gb acc num :
NM_014476.5
ncbi summary :
The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. [provided by RefSeq, Apr 2012]
uniprot summary :
May play a role in the organization of actin filament arrays within muscle cells.