product summary
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company name :
MyBioSource
product type :
antibody
product name :
CUL5 Antibody
catalog :
MBS853458
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
immunohistochemistry
more info or order :
product information
catalog number :
MBS853458
products type :
Antibody
products full name :
CUL5 Antibody
products short name :
CUL5
other names :
Homo sapiens cullin 5 (CUL5), mRNA; Cullin-5; cullin-5; CUL-5; Vasopressin-activated calcium-mobilizing receptor-1; vasopressin-activated calcium-mobilizing receptor 1; Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1); cullin 5; Vasopressin-activated calcium-mobilizing receptor 1; VACM-1
products gene name :
CUL5
other gene names :
CUL5; CUL5; VACM1; VACM-1; VACM1; CUL-5; VACM-1
uniprot entry name :
CUL5_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
6408
form :
Lyophilized CUL5 antibody purified by peptide affinity column containing 2% BSA and 0.02% NaN3
concentration :
100ug/200ul
tested application :
Immunohistochemistry (IHC)
app notes :
Peptide ELISA titer: 1:40,000-1:80,000. Immunohistochemistry: 1:50-500. Optimal dilutions/concentrations should be determined by the end user.
other info1 :
Source Note: Rabbit polyclonal CUL5 (1) antibody was raised against a peptide from a peptide from near the C terminal residues of human CUL5 protein. Reactivity Note: Not yet tested in other species.
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
(1) An,P., Duggal,P., Wang,L.H., O'Brien,S.J., et al.Polymorphisms of CUL5 are associated with CD4+ T cell loss in HIV-1 infected individuals.PLoS Genet. 3 (1), E19 (2007)
ncbi gi num :
67514034
ncbi acc num :
NP_003469.2
ncbi gb acc num :
NM_003478
ncbi mol weight :
90,955 Da
ncbi pathways :
Adaptive Immune System Pathway (366160); Antigen Processing: Ubiquitination Proteasome Degradation Pathway (366162); Class I MHC Mediated Antigen Processing Presentation Pathway (366161); Disease Pathway (530764); ECS Complex Pathway (413455); ECS Complex Pathway (468394); HIV Infection Pathway (105983); Host Interactions Of HIV Factors Pathway (106010); Immune System Pathway (106386); Signal Transduction Pathway (477114)
uniprot summary :
CUL5: a component of E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to be involved proteasomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. Member of the cullin family. Protein type: Ubiquitin conjugating system. Chromosomal Location of Human Ortholog: 11q22.3. Cellular Component: Cul5-RING ubiquitin ligase complex; plasma membrane; cytosol; nucleus. Molecular Function: protein binding; protein heterodimerization activity; ubiquitin protein ligase binding; calcium channel activity; receptor activity. Biological Process: ubiquitin-dependent protein catabolic process; negative regulation of cell proliferation; cell proliferation; cytosolic calcium ion homeostasis; viral reproduction; protein ubiquitination; cell cycle arrest; response to osmotic stress; G1/S transition of mitotic cell cycle
size1 :
0.1 mg
price1 :
290 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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