MMP-7 Antibody | MyBioSource MBS853438 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

MMP-7 Antibody

catalog :

MBS853438

quantity :

0.1 mg

price :

215 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS853438

products type :

Antibody

products full name :

MMP-7 Antibody

products short name :

MMP-7

products name syn :

PUMP1; PUTATIVE METALLOPROTEINASE I; matrix metalloproteinase 7 (matrilysin; uterine)

other names :

matrilysin preproprotein; Matrilysin; matrilysin; matrin; pump-1 protease; uterine matrilysin; uterine metalloproteinase; matrix metalloproteinase-7; matrix metalloproteinase 7 (matrilysin, uterine); matrix metallopeptidase 7 (matrilysin, uterine); Matrin; Matrix metalloproteinase-7; MMP-7; Pump-1 protease; Uterine metalloproteinase

products gene name :

MMP-7

other gene names :

MMP7; MMP7; MMP-7; MPSL1; PUMP-1; MPSL1; PUMP1; MMP-7

uniprot entry name :

MMP7_HUMAN

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

267

specificity :

MMP-7 antibody detects endogenous levels of total MMP-7 protein.

purity :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

form :

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

concentration :

100ug/100ul

storage stability :

Store at -20 degree C for 1 year

tested application :

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

app notes :

WB: 1:500~1:1000, IHC: 1:50~1:100, ELISA: 1:5000

other info2 :

Immunogen: The antiserum was produced against synthesized peptide derived from human MMP-7. Pathway: Translation

products categories :

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

products references :

Lydia E. Wroblewski, J. Cell Sci., Jul 2003; 116: 3017. Andrea Varro, Am J Physiol Gastrointest Liver Physiol, Apr 2007; 292: G1133 - G1140. Wei-Hsuan Yu, Genes & Dev., Feb 2002; 16: 307. Nick Di Girolamo, Invest. Ophthalmol. Vis. Sci., Aug 2001; 42: 1963.

ncbi gi num :

4505219

ncbi acc num :

NP_002414.1

ncbi gb acc num :

NM_002423.3

uniprot acc num :

P09237

ncbi mol weight :

29,677 Da

ncbi pathways :

AGE/RAGE Pathway (698754); Activation Of Matrix Metalloproteinases Pathway (576264); Alpha6-Beta4 Integrin Signaling Pathway (198807); Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway (730306); Collagen Degradation Pathway (730309); Collagen Formation Pathway (645288); Degradation Of The Extracellular Matrix Pathway (576263); Extracellular Matrix Organization Pathway (576262); Matrix Metalloproteinases Pathway (198900); Syndecan-1-mediated Signaling Events Pathway (138046)

ncbi summary :

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]

uniprot summary :

MMP7: Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. Belongs to the peptidase M10A family. Protein type: Protease; EC 3.4.24.23; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 11q22.2. Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region. Molecular Function: zinc ion binding; metalloendopeptidase activity. Biological Process: response to drug; extracellular matrix disassembly; collagen catabolic process; defense response to Gram-positive bacterium; extracellular matrix organization and biogenesis; antibacterial peptide biosynthetic process; proteolysis; defense response to Gram-negative bacterium; antibacterial peptide secretion; regulation of cell proliferation

size1 :

0.1 mg

price1 :

215 USD

more info or order :

MyBioSource product webpage