product summary
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company name :
MyBioSource
product type :
antibody
product name :
CCR2
catalog :
MBS8534078
quantity :
0.1 mL
price :
280 USD
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry, FACS
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS8534078
products type :
Antibody
products full name :
CCR2
products short name :
[CCR2]
other names :
[C-C chemokine receptor type 2 isoform A; C-C chemokine receptor type 2; C-C chemokine receptor type 2; C-C motif chemokine receptor 2; Monocyte chemoattractant protein 1 receptor; MCP-1-R; CD_antigen: CD192]
products gene name :
[CCR2]
products gene name syn :
[C-C CKR-2; CC-CKR-2; CCR-2; CCR2; MCP-1-R; CCR2; CMKBR2]
other gene names :
[CCR2; CCR2; CKR2; CCR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2; CMKBR2; C-C CKR-2; CC-CKR-2; CCR-2; CCR2; MCP-1-R]
clonality :
Monoclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
374
purity :
ProA affinity purified
form :
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
storage stability :
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
other info1 :
Immunogen: Recombinant Protein
products description :
C-C chemokine receptor type 2, Monocyte chemoattractant protein 1 receptor, CD_antigen: CD192
ncbi gi num :
183979980
ncbi acc num :
NP_001116513.2
ncbi gb acc num :
NM_001123041.2
uniprot acc num :
P41597
ncbi pathways :
Beta Defensins Pathway (530759); Chemokine Receptors Bind Chemokines Pathway (106359); Chemokine Signaling Pathway (99051); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Defensins Pathway (530757); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548)
ncbi summary :
The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]
uniprot summary :
Receptor for the CCL2, CCL7 and CCL13 chemokines (PubMed:23408426). Receptor for the beta-defensin DEFB106A/DEFB106B (PubMed:23938203). Transduces a signal by increasing intracellular calcium ion levels (). Upon CCL2 ligation, mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (Probable).
size1 :
0.1 mL
price1 :
280 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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