product summary
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company name :
MyBioSource
product type :
antibody
product name :
Cathepsin D
catalog :
MBS8533837
quantity :
0.1 mL
price :
280 USD
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, FACS
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS8533837
products type :
Antibody
products full name :
Cathepsin D
products short name :
[Cathepsin D]
products name syn :
[Cathepsin D; Cathepsin D light chain; Cathepsin D heavy chain]
other names :
[cathepsin D preproprotein; Cathepsin D; cathepsin D; cathepsin D]
products gene name :
[CTSD]
other gene names :
[CTSD; CTSD; CPSD; CLN10; HEL-S-130P; CPSD]
clonality :
Monoclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
412
purity :
ProA affinity purified
storage stability :
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
other info1 :
Immunogen: Recombinant Protein. Buffer: 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
ncbi gi num :
4503143
ncbi acc num :
NP_001900.1
ncbi gb acc num :
NM_001909.4
uniprot acc num :
P07339
ncbi pathways :
Adaptive Immune System Pathway (366160); Ceramide Signaling Pathway (138023); Degradation Of Collagen Pathway (730309); Degradation Of The Extracellular Matrix Pathway (576263); Direct P53 Effectors Pathway (137939); Extracellular Matrix Organization Pathway (576262); Immune System Pathway (106386); LKB1 Signaling Events Pathway (137957); Lysosome Pathway (99052); Lysosome Pathway (96865)
ncbi summary :
This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]
uniprot summary :
Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation (PubMed:27333034). Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
size1 :
0.1 mL
price1 :
280 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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