catalog number :
MBS853233
products full name :
VIPR2 Antibody
products short name :
[VIPR2]
products name syn :
[Vasoactive intestinal polypeptide receptor 2 [Precursor]; VIP-R-2; Pituitary adenylate cyclase-activating polypeptide type III receptor; PACAP type III receptor; PACAP-R-3; Helodermin-preferring VIP receptor; VIP2R]
other names :
[vasoactive intestinal polypeptide receptor 2 isoform 2; Vasoactive intestinal polypeptide receptor 2; vasoactive intestinal polypeptide receptor 2; vasoactive intestinal peptide receptor 2; Helodermin-preferring VIP receptor; Pituitary adenylate cyclase-activating polypeptide type III receptor; PACAP type III receptor; PACAP-R-3; PACAP-R3; VPAC2]
products gene name :
[VIPR2]
other gene names :
[VIPR2; VIPR2; VPAC2; VPAC2R; VIP-R-2; VPCAP2R; PACAP-R3; DUP7q36.3; PACAP-R-3; C16DUPq36.3; VIP2R; VIP-R-2; PACAP type III receptor; PACAP-R-3; PACAP-R3]
reactivity :
Human, Mouse, Rat
specificity :
VIPR2 antibody detects endogenous levels of total VIPR2 protein.
purity :
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at-20 degree C for 1 year.
tested application :
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
app notes :
WB: 1:500~1:1000. IF: 1:100~1:500. ELISA: 1:1000
image1 heading :
Testing Data
image2 heading :
Western Blot (WB)
other info1 :
Immunogen: The antiserum was produced against synthesized peptide derived from internal of human VIPR2.
products categories :
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
products references :
Svoboda M., Biochem. Biophys. Res. Commun. 205:1617-1624(1994). Mackay M., Genomics 37:345-353(1996). Wei Y., J. Neuroendocrinol. 8:811-817(1996).
ncbi acc num :
NP_001291451.1
ncbi gb acc num :
NM_001304522.1
ncbi mol weight :
46,756 Da
ncbi pathways :
G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCRs, Class B Secretin-like Pathway (198781); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); SIDS Susceptibility Pathways (198901); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356); CAMP Signaling Pathway (1017634); CAMP Signaling Pathway (1019520)
ncbi summary :
This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. [provided by RefSeq, Aug 2011]
uniprot summary :
This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C.