catalog number :
MBS853219
products full name :
THBS1 Antibody
products short name :
THBS1
other names :
Homo sapiens thrombospondin 1 (THBS1), mRNA; Thrombospondin-1; thrombospondin-1; thrombospondin-1p180; thrombospondin 1
products gene name :
THBS1
other gene names :
THBS1; THBS1; TSP; THBS; TSP1; TSP-1; THBS-1; TSP; TSP1
uniprot entry name :
TSP1_HUMAN
reactivity :
Human, Mouse, Rat
form :
Lyophilized THBS1 antibody purified by peptide affinity column containing 2% BSA and 0.02% NaN3
concentration :
100ug/200ul
tested application :
Immunohistochemistry (IHC)
app notes :
Peptide ELISA titer: 1:40,000-1:80,000. Immunohistochemistry: 1:50-200. Optimal dilutions/concentrations should be determined by the end user.
other info1 :
Source Note: Rabbit polyclonal THBS1 (1) antibody was raised against a peptide from near the N terminal residues of human THBS1 protein. Reactivity Note: Not yet tested in other species.
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
(1) Martin-Manso,G., Galli,S., Ridnour,L.A., et al.Thrombospondin 1 promotes tumor macrophage recruitment and enhances tumor cell cytotoxicity of differentiated U937 cells.Cancer Res. 68 (17), 7090-7099 (2008)
ncbi acc num :
NP_003237.2
ncbi gb acc num :
NM_003246
ncbi mol weight :
120,148 Da
ncbi pathways :
Bladder Cancer Pathway 83115!!Bladder Cancer Pathway 527!!ECM-receptor Interaction Pathway 83068!!ECM-receptor Interaction Pathway 479!!Extracellular Matrix Organization Pathway 576262!!Focal Adhesion Pathway 198795!!Focal Adhesion Pathway 83067!!Focal Adhesion Pathway 478!!Hemostasis Pathway 106028!!Inflammatory Response Pathway 198766
ncbi summary :
The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008]