catalog number :
MBS8531852
products full name :
MGT5A Polyclonal Antibody
products short name :
[MGT5A]
products name syn :
[Alpha-1, 6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; EC 2.4.1.155; Alpha-mannoside beta-1, 6-N-acetylglucosaminyltransferase; GlcNAc-T V; GNT-V; Mannoside acetylglucosaminyltransferase 5; N-acetylglucosaminyl-transferase V; MGAT5; GGNT5]
other names :
[alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase; Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase; GlcNAc-T V; GNT-V; Mannoside acetylglucosaminyltransferase 5; N-acetylglucosaminyl-transferase V]
products gene name :
[MGT5A]
other gene names :
[MGAT5; MGAT5; GNT-V; GNT-VA; GGNT5; GNT-V]
reactivity :
Human, Mouse, Rat
specificity :
MGT5A Polyclonal Antibody detects endogenous levels of protein.
purity :
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
storage stability :
Store at-20 degree C for 1 year.
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
WB: 1:500-2000. ELISA: 1:5000-20000
other info1 :
Immunogen: Synthesized peptide derived from human protein. at AA range: 551-600
ncbi acc num :
NP_002401.1
ncbi gb acc num :
NM_002410.4
ncbi pathways :
Asparagine N-linked Glycosylation Pathway (161013); Metabolic Pathways (132956); Metabolism Of Proteins Pathway (106230); N-Glycan Antennae Elongation Pathway (187226); N-Glycan Biosynthesis Pathway (82975); N-Glycan Biosynthesis Pathway (345); N-glycan Antennae Elongation In The Medial/trans-Golgi Pathway (187223); N-glycan Biosynthesis, Complex Type Pathway (413356); N-glycan Biosynthesis, Complex Type Pathway (468278); Post-translational Protein Modification Pathway (161012)
ncbi summary :
The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies. [provided by RefSeq, Oct 2011]
uniprot summary :
Catalyzes the addition of N-acetylglucosamine in beta 1-6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides.