Aldolase A Antibody | MyBioSource MBS853180 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Aldolase A Antibody

catalog :

MBS853180

quantity :

0.1 mg

price :

355 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS853180

products type :

Antibody

products full name :

Aldolase A Antibody

products short name :

Aldolase A

other names :

fructose-bisphosphate aldolase A isoform 1; Fructose-bisphosphate aldolase A; fructose-bisphosphate aldolase A; muscle-type aldolase; lung cancer antigen NY-LU-1; fructose-1,6-bisphosphate triosephosphate-lyase; epididymis secretory sperm binding protein Li 87p; aldolase A, fructose-bisphosphate; Lung cancer antigen NY-LU-1; Muscle-type aldolase

other gene names :

ALDOA; ALDOA; ALDA; GSD12; HEL-S-87p; ALDA

uniprot entry name :

ALDOA_HUMAN

clonality :

Monoclonal

isotype :

IgG1

host :

Mouse

sequence length :

364

specificity :

Anti-Aldolase A recognizes Aldolase A expression in Hela whole cell lysate.

form :

Each vial contains 100 ug IgG in 100 ul of citrate-tris-HCl buffer pH7.0 with 0.02% Proclin 300.

storage stability :

The antibody may be stored at -20 degree C for one year in its original formulation. Additionally, antibody may be stored at 2 degree C to 8 degree C for up to 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles of the diluted antibody.

tested application :

ELISA (EIA),Western Blot (WB-Ce)

other info1 :

Source Note: Purified mouse monoclonal antibody generated using Yeast expressed recombinant protein Aldolase A as immunogen.

other info2 :

Immunogen: Recombinant protein corresponding to full length Aldolase A.

products categories :

Plant antibody

ncbi gi num :

34577110

ncbi acc num :

NP_908930.1

ncbi gb acc num :

NM_184041

ncbi mol weight :

45,261 Da

ncbi pathways :

Biosynthesis Of Amino Acids Pathway (790012); Biosynthesis Of Amino Acids Pathway (795174); Carbon Metabolism Pathway (814926); Carbon Metabolism Pathway (817567); Disease Pathway (530764); Fructose And Mannose Metabolism Pathway (82930); Fructose And Mannose Metabolism Pathway (291); Gluconeogenesis Pathway (106204); Gluconeogenesis, Oxaloacetate = Fructose-6P Pathway (413342); Gluconeogenesis, Oxaloacetate = Fructose-6P Pathway (468196)

ncbi summary :

The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Aug 2011]

uniprot summary :

ALDOA: a glycolytic enzyme that catalyzes D-fructose 1,6-bisphosphate - glycerone phosphate + D-glyceraldehyde 3-phosphate. Three forms of aldolase are found in vertebrates - aldolase A in muscle, aldolase B in liver and aldolase C in brain. Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - fructose and mannose; Mitochondrial; EC 4.1.2.13; Carbohydrate Metabolism - pentose phosphate pathway; Lyase. Chromosomal Location of Human Ortholog: 16p11.2. Cellular Component: I band; extracellular space; membrane; extracellular region; M band; nucleus; cytosol; actin cytoskeleton. Molecular Function: tubulin binding; identical protein binding; protein binding; cytoskeletal protein binding; fructose-bisphosphate aldolase activity; actin binding. Biological Process: platelet activation; glycolysis; striated muscle contraction; glucose metabolic process; actin filament organization; pathogenesis; protein homotetramerization; gluconeogenesis; muscle maintenance; regulation of cell shape; fructose 1,6-bisphosphate metabolic process; platelet degranulation; ATP biosynthetic process; carbohydrate metabolic process; blood coagulation; fructose metabolic process. Disease: Glycogen Storage Disease Xii

size1 :

0.1 mg

price1 :

355 USD

more info or order :

MyBioSource product webpage