catalog number :
MBS8531722
products full name :
DLL3 Polyclonal Antibody
products short name :
[DLL3]
products name syn :
[Delta-like protein 3; Drosophila Delta homolog 3; Delta3; DLL3]
other names :
[delta-like protein 3 isoform 1; Delta-like protein 3; delta-like protein 3; delta like canonical Notch ligand 3; Drosophila Delta homolog 3; Delta3]
products gene name :
[DLL3]
other gene names :
[DLL3; DLL3; SCDO1; Delta3]
reactivity :
Human, Mouse, Rat
purity :
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
storage stability :
Store at-20°C/1 year.
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
WB: 1:500-2000. ELISA: 1:5000-20000
other info1 :
Immunogen: Synthesized peptide derived from human protein. at AA range: 510-590
ncbi acc num :
NP_058637.1
ncbi gb acc num :
NM_016941.3
ncbi pathways :
Neural Crest Differentiation Pathway (672460); Notch Signaling Pathway (198891); Notch Signaling Pathway (1084758); Notch Signaling Pathway (1108221); Notch Signaling Pathway (83062); Notch Signaling Pathway (169345); Notch Signaling Pathway (473)
ncbi summary :
This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm ().