LAMA5 Antibody | MyBioSource MBS853115 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

LAMA5 Antibody

catalog :

MBS853115

quantity :

0.1 mg

price :

215 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS853115

products type :

Antibody

products full name :

LAMA5 Antibody

products short name :

LAMA5

products name syn :

Laminin subunit alpha-5; KIAA0533; KIAA1907

other names :

laminin subunit alpha-5; Laminin subunit alpha-5; laminin subunit alpha-5; laminin alpha-5 chain; laminin-10 subunit alpha; laminin-11 subunit alpha; laminin-15 subunit alpha; laminin, alpha 5; Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha

products gene name :

LAMA5

other gene names :

LAMA5; LAMA5; KIAA0533; KIAA1907

uniprot entry name :

LAMA5_HUMAN

host :

Rabbit

reactivity :

Human, Mouse

sequence length :

3695

specificity :

LAMA5 antibody detects endogenous levels of total LAMA5 protein.

purity :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

form :

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

storage stability :

Store at -20 degree C for 1 year

tested application :

Immunohistochemistry (IHC), ELISA (EIA)

app notes :

IHC: 1:50~1:100, ELISA: 1:20000

other info1 :

Reactivity Note: Human (Identities = 100%, Positives = 100%); Mouse (Identities = 92%, Positives = 100%)

other info2 :

Immunogen: The antiserum was produced against synthesized peptide derived from internal of human LAMA5. Pathway: Adhesion

products categories :

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

products references :

Deloukas P., ure 414:865-871(2001). Nagase T., DNA Res. 8:179-187(2001). Nagase T., DNA Res. 5:31-39(1998). ------------------------------------------------------------------------------------------------------------------------------------------

ncbi gi num :

21264602

ncbi acc num :

NP_005551.3

ncbi gb acc num :

NM_005560.4

uniprot acc num :

O15230

ncbi mol weight :

399,737 Da

ncbi pathways :

Alpha6-Beta4 Integrin Signaling Pathway (198807); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Degradation Of The Extracellular Matrix Pathway (576263); ECM Proteoglycans Pathway (833812); ECM-receptor Interaction Pathway (83068); ECM-receptor Interaction Pathway (479); Extracellular Matrix Organization Pathway (576262); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067)

ncbi summary :

This gene encodes one of the vertebrate laminin alpha chains. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. The protein encoded by this gene is the alpha-5 subunit of of laminin-10 (laminin-511), laminin-11 (laminin-521) and laminin-15 (laminin-523). [provided by RefSeq, Jun 2013]

uniprot summary :

LAMA5: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Protein type: Secreted; Motility/polarity/chemotaxis; Extracellular matrix; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 20q13.2-q13.3. Cellular Component: extracellular matrix; extracellular space; laminin-5 complex; laminin-1 complex; laminin-10 complex; extracellular region; basement membrane; basal lamina; nucleus. Molecular Function: integrin binding; structural molecule activity. Biological Process: integrin-mediated signaling pathway; regulation of cell adhesion; focal adhesion formation; endothelial cell differentiation; extracellular matrix organization and biogenesis; muscle development; cell migration; regulation of embryonic development; cell recognition; cytoskeleton organization and biogenesis; regulation of cell migration; regulation of cell proliferation; odontogenesis of dentine-containing teeth; extracellular matrix disassembly; cell proliferation; embryonic development; morphogenesis of embryonic epithelium; hair follicle development; ureteric bud branching; cilium biogenesis; angiogenesis; cell differentiation; neural crest cell migration; morphogenesis of a polarized epithelium; lung development

size1 :

0.1 mg

price1 :

215 USD

more info or order :

MyBioSource product webpage