FGF13 Antibody | MyBioSource MBS853104 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

FGF13 Antibody

catalog :

MBS853104

quantity :

0.1 mg

price :

215 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS853104

products type :

Antibody

products full name :

FGF13 Antibody

products short name :

FGF13

products name syn :

Fibroblast growth factor 13; FGF-13; Fibroblast growth factor homologous factor 2; FHF-2

other names :

fibroblast growth factor 13 isoform 4; Fibroblast growth factor 13; fibroblast growth factor 13; fibroblast growth factor homologous factor 2; fibroblast growth factor 13; Fibroblast growth factor homologous factor 2; FHF-2

products gene name :

FGF13

other gene names :

FGF13; FGF13; FGF2; FHF2; FHF-2; FGF-13; FHF2; FGF-13; FHF-2

uniprot entry name :

FGF13_HUMAN

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

199

specificity :

FGF13 antibody detects endogenous levels of total FGF13 protein.

purity :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

form :

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

storage stability :

Store at -20 degree C for 1 year

tested application :

Western Blot (WB), ELISA (EIA)

app notes :

WB: 1:500~1:1000, ELISA: 1:5000

other info1 :

Reactivity Note: Human (Identities = 100%, Positives = 100%); Mouse (Identities = 100%, Positives = 100%); Rat (Identities = 100%, Positives = 100%)

other info2 :

Immunogen: The antiserum was produced against synthesized peptide derived from internal of human FGF13. Pathway: Growth Factors

products categories :

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

products references :

Smallwood P.M., Proc. Natl. Acad. Sci. U.S.A. 93:9850-9857(1996). Gecz J., Hum. Genet. 104:56-63(1999). Ross M.T., Nature 434:325-337(2005). -----------------------------------------------------------------------------------------------------------

ncbi gi num :

213417606

ncbi acc num :

NP_001132970.1

ncbi gb acc num :

NM_001139498.1

uniprot acc num :

Q92913

ncbi mol weight :

25,607 Da

ncbi pathways :

MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Melanoma Pathway (83114); Melanoma Pathway (526); PI3K-Akt Signaling Pathway (692234); PI3K-Akt Signaling Pathway (692979); Pathways In Cancer (83105); Rap1 Signaling Pathway (868086); Rap1 Signaling Pathway (878042); Ras Signaling Pathway (868085)

ncbi summary :

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008]

uniprot summary :

FGF13: Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Belongs to the heparin-binding growth factors family. 5 isoforms of the human protein are produced by alternative splicing. Protein type: Cell development/differentiation; Nucleolus. Chromosomal Location of Human Ortholog: Xq26.3. Cellular Component: microtubule; neuron projection; growth cone; axon; dendrite; cytoplasm; plasma membrane; extracellular region; nucleolus; nucleus; filopodium. Molecular Function: protein binding; growth factor activity; sodium channel regulator activity; microtubule binding; beta-tubulin binding; protein kinase activator activity. Biological Process: nervous system development; negative regulation of microtubule depolymerization; establishment of neuroblast polarity; hippocampus development; MAPKKK cascade; neuron migration; learning; negative regulation of collateral sprouting; signal transduction; memory; cerebral cortex cell migration; cell-cell signaling; positive regulation of protein kinase activity; microtubule polymerization

size1 :

0.1 mg

price1 :

215 USD

more info or order :

MyBioSource product webpage