catalog number :
MBS852992
products full name :
PKR1 Antibody
products short name :
PKR1
products name syn :
Prokineticin receptor 1; PK-R1; G-protein coupled receptor 73; GPR73a; G-protein coupled receptor ZAQ; PROKR1; GPR73; PKR1
other names :
prokineticin receptor 1; Prokineticin receptor 1; prokineticin receptor 1; PK-R1; G protein-coupled receptor 73; G-protein coupled receptor 73; G protein-coupled receptor ZAQ; G-protein coupled receptor ZAQ; prokineticin receptor 1; G-protein coupled receptor 73; G-protein coupled receptor ZAQ; GPR73a
products gene name :
PKR1
other gene names :
PROKR1; PROKR1; ZAQ; PKR1; GPR73; GPR73a; GPR73; PKR1; PK-R1
uniprot entry name :
PKR1_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
PKR1 antibody detects endogenous levels of total PKR1 protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20 degree C for 1 year
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
WB: 1:500~1:1000, ELISA: 1:20000
other info2 :
Immunogen: The antiserum was produced against synthesized peptide derived from internal of human PKR1. Pathway: GPCR
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
Masuda Y., Biochem. Biophys. Res. Commun. 293:396-402(2002). Soga T., Biochim. Biophys. Acta 1579:173-179(2002). Lin D.C.-H., J. Biol. Chem. 277:19276-19280(2002).
ncbi acc num :
NP_620414.1
ncbi gb acc num :
NM_138964.2
ncbi mol weight :
44,770 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Gastrin-CREB Signalling Pathway Via PKC And MAPK (645295); Peptide Ligand-binding Receptors Pathway (106358); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)
uniprot summary :
PROKR1: Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. Belongs to the G-protein coupled receptor 1 family. Protein type: GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR. Chromosomal Location of Human Ortholog: 2p13.1. Cellular Component: plasma membrane; integral to membrane. Molecular Function: neuropeptide Y receptor activity. Biological Process: neuropeptide signaling pathway; negative regulation of apoptosis