catalog number :
MBS852720
products full name :
Stefin A Antibody
products short name :
[Stefin A]
products name syn :
[STF1; STFA; cystatin A (stefin A), cystatin AS]
other names :
[cystatin-A; Cystatin-A; cystatin-A; cystatin A; Cystatin-AS; Stefin-A]
products gene name :
[STFA]
other gene names :
[CSTA; CSTA; AREI; PSS4; STF1; STFA; STF1; STFA]
specificity :
Stefin A antibody detects endogenous levels of total Stefin A protein.
purity :
The antibody was Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Rabbit IgG in phosphate buffered saline (without Mg 2+ and Ca 2+ ), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at-20 degree C for 1 year.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
app notes :
WB: 1:500~1:1000. IHC: 1:50~1:100. IF: 1:100~1:500. ELISA: 1:5000
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Western Blot (WB)
image3 heading :
Immunofluorescence (IF)
other info1 :
Immunogen: The antiserum was produced against synthesized peptide derived from C-terminal of human Stefin A.
products categories :
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
products references :
Janko Kos, Clin. Cancer Res., Feb 2000; 6: 505. Wendong Li, Clin. Cancer Res., Dec 2005; 11: 8753-8762. I Mlinaric-Rascan, Am. J. Pathol., Oct 1994; 145: 902.
ncbi acc num :
NP_005204.1
ncbi gb acc num :
NM_005213.3
ncbi summary :
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer. [provided by RefSeq, Jul 2008]
uniprot summary :
This is an intracellular thiol proteinase inhibitor. Has an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis.