ABCC3 Antibody | MyBioSource MBS852567 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

ABCC3 Antibody

catalog :

MBS852567

quantity :

0.1 mg

price :

215 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS852567

products type :

Antibody

products full name :

ABCC3 Antibody

products short name :

ABCC3

products name syn :

Canalicular multispecific organic anion transporter 2; ATP-binding cassette sub-family C member 3; Multi-specific organic anion transporter D; MOAT-D; Multidrug resistance-associated protein 3 ; ABCC3 ; CMOAT2; MLP2; MRP3

other names :

canalicular multispecific organic anion transporter 2 isoform 2; Canalicular multispecific organic anion transporter 2; canalicular multispecific organic anion transporter 2; multidrug resistance associated protein; multidrug resistance-associated protein 3; ATP-binding cassette sub-family C member 3; multi-specific organic anion transporter D; canicular multispecific organic anion transporter; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; ATP-binding cassette sub-family C member 3; Multi-specific organic anion transporter D; MOAT-D; Multidrug resistance-associated protein 3

products gene name :

ABCC3

other gene names :

ABCC3; ABCC3; MLP2; MRP3; ABC31; MOAT-D; cMOAT2; EST90757; CMOAT2; MLP2; MRP3; MOAT-D

uniprot entry name :

MRP3_HUMAN

host :

Rabbit

reactivity :

Human

sequence length :

572

specificity :

ABCC3 antibody detects endogenous levels of total ABCC3 protein.

purity :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

form :

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

storage stability :

Store at -20 degree C for 1 year

tested application :

Western Blot (WB), ELISA (EIA)

app notes :

WB: 1:500~1:1000, ELISA: 1:5000

other info1 :

Reactivity Note: Human (Identities = 100%, Positives = 100%)

other info2 :

Immunogen: The antiserum was produced against synthesized peptide derived from internal of human ABCC3. Pathway: Cancer/Apoptosis

products categories :

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

products references :

Uchiumi T., em. Biophys. Res. Commun. 252:103-110(1998). Kiuchi Y., FEBS Lett. 433:149-152(1998). linsky M.G., J. Natl. Cancer Inst. 90:1735-1741(1998). -----------------------------------------------------------------------------------------------------------------------------------------

ncbi gi num :

221316556

ncbi acc num :

NP_001137542.1

ncbi gb acc num :

NM_001144070.1

uniprot acc num :

O15438

ncbi mol weight :

64,632 Da

ncbi pathways :

ABC Transporters Pathway (83035); ABC Transporters Pathway (436); ABC-family Proteins Mediated Transport Pathway (106573); Bile Acid And Bile Salt Metabolism Pathway (106144); Bile Secretion Pathway (193146); Bile Secretion Pathway (193095); Codeine And Morphine Metabolism Pathway (198831); Drug Induction Of Bile Acid Pathway (698755); Fluoropyrimidine Activity Pathway (198778); Metabolism Pathway (477135)

ncbi summary :

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

uniprot summary :

ABCC3: May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 5 isoforms of the human protein are produced by alternative splicing. Protein type: Transporter; Membrane protein, multi-pass; Transporter, ABC family; Membrane protein, integral. Chromosomal Location of Human Ortholog: 17q22. Cellular Component: membrane; integral to plasma membrane; plasma membrane. Molecular Function: ATPase activity, coupled to transmembrane movement of substances; organic anion transmembrane transporter activity; ATP binding. Biological Process: bile acid and bile salt transport; bile acid metabolic process; transport; transmembrane transport

size1 :

0.1 mg

price1 :

215 USD

more info or order :

MyBioSource product webpage