catalog number :
MBS8523504
products full name :
Laminin alpha-1 Polyclonal Antibody
products short name :
[Laminin alpha-1]
products name syn :
[LAMA1; LAMA; Laminin subunit alpha-1; Laminin A chain;Laminin-1 subunit alpha; Laminin-3 subunit alpha; S-lamininsubunit alpha; S-LAM alpha]
other names :
[laminin subunit alpha-1; Laminin subunit alpha-1; laminin subunit alpha-1; laminin subunit alpha 1; Laminin A chain; Laminin-1 subunit alpha; Laminin-3 subunit alpha; S-laminin subunit alpha; S-LAM alpha]
other gene names :
[LAMA1; LAMA1; LAMA; PTBHS; S-LAM-alpha; LAMA; S-LAM alpha]
specificity :
Laminin alpha-1 Polyclonal Antibody detects endogenous levels ofLaminin ?-1 protein
purity :
The antibody was affinity-purified from rabbit antiserum byaffinity-chromatography using epitope-specific immunogen.
form :
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
storage stability :
Store at -20°C/1 year
tested application :
Immunofluorescence (IF), ELISA (EIA)
other info1 :
Immunogen: Synthesized peptide derived from the C-terminal region ofhuman Laminin ?-1. at AA rangle: 2470-2550.
ncbi acc num :
NP_005550.2
ncbi gb acc num :
NM_005559.3
ncbi mol weight :
337.158
ncbi pathways :
Alpha6-Beta4 Integrin Signaling Pathway (198807); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Axon Guidance Pathway (105688); Developmental Biology Pathway (477129); ECM-receptor Interaction Pathway (83068); ECM-receptor Interaction Pathway (479); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478)
ncbi summary :
This gene encodes one of the alpha 1 subunits of laminin. The laminins are a family of extracellular matrix glycoproteins that have a heterotrimeric structure consisting of an alpha, beta and gamma chain. These proteins make up a major component of the basement membrane and have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Mutations in this gene may be associated with Poretti-Boltshauser syndrome. [provided by RefSeq, Sep 2014]
uniprot summary :
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.