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company name :
MyBioSource
product type :
antibody
product name :
Caspase 9 (Cleaved-Asp353) Antibody
catalog :
MBS852276
quantity :
0.1 mg
price :
215 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
product information
catalog number :
MBS852276
products type :
Antibody
products full name :
Caspase 9 (Cleaved-Asp353) Antibody
products short name :
Caspase 9
products name syn :
APAF-3; Apoptotic protease Mch-6; Apoptotic protease activating factor 3; CASP-9; Caspase-9; Caspase-9 precursor; EC 3.4.22.-; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; RNCASP9
other names :
Caspase9S; Caspase
other gene names :
Casp9
uniprot entry name :
Q9R0S9_MOUSE
host :
Rabbit
reactivity :
Mouse, Rat
sequence length :
393
specificity :
Caspase 9 (cleaved-Asp353) antibody detects endogenous levels of fragment of activated Caspase 9 resulting from cleavage adjacent to Asp 353.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
100ug/100ul
storage stability :
Store at -20 degree C for 1 year
tested application :
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
app notes :
WB: 1:500~1:1000, IHC: 1:50~1:100, ELISA: 1:20000
other info2 :
Immunogen: The antiserum was produced against synthesized peptide derived from mouse Caspase 9. All Sites: Mouse: Asp353; Rat: Asp353. Pathway: Cleaved-specific
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
Tara Sotsky Kent, Ann. Surg. Oncol., Feb 2004; 11: 192. Yuanming Hu, J. Biol. Chem., Dec 1998; 273: 33489. C.S. Thota, Biol Reprod, Dec 2005; 73: 1191 - 1198. Jonathan H. Lieman, J. Biol. Chem., Mar 2005; 280: 10484 - 10490.
ncbi gi num :
81872787
ncbi acc num :
Q9R0S9
uniprot acc num :
Q9R0S9
ncbi mol weight :
42,975 Da
uniprot summary :
CASP9: a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two isoforms. Protein type: EC 3.4.22.62; Protease; Apoptosis. Cellular Component: mitochondrion; cytoplasm; cytosol; nucleus; apoptosome. Molecular Function: peptidase activity; protein binding; cysteine-type endopeptidase activity; SH3 domain binding; protein kinase binding; cysteine-type peptidase activity. Biological Process: caspase activation; apoptosis; positive regulation of apoptosis; DNA damage response, signal transduction; response to lipopolysaccharide; proteolysis; response to organic cyclic substance; response to estradiol stimulus; response to antibiotic; DNA damage response, signal transduction resulting in induction of apoptosis; positive regulation of neuron apoptosis; response to cobalt ion; response to DNA damage stimulus; response to UV; aging
size1 :
0.1 mg
price1 :
215 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
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