catalog number :
MBS852233
products full name :
Cytokeratin-1/Keratin-1 Antibody
products short name :
Cytokeratin-1/Keratin-1
other names :
Homo sapiens keratin 1 (KRT1), mRNA; Keratin, type II cytoskeletal 1; keratin, type II cytoskeletal 1; CK-1; cytokeratin 1; cytokeratin-1; 67 kDa cytokeratin; hair alpha protein; type-II keratin Kb1; epidermolytic hyperkeratosis 1; keratin 1; 67 kDa cytokeratin; Cytokeratin-1; CK-1; Hair alpha protein; Keratin-1; K1; Type-II keratin Kb1
other gene names :
KRT1; KRT1; K1; CK1; EHK; EHK1; EPPK; KRT1A; NEPPK; KRTA; CK-1; K1
uniprot entry name :
K2C1_HUMAN
reactivity :
Human, Mouse, Rat
form :
Lyophilized anti- Cytokeratin-1 antibody purified by peptide affinity column containing 1% BSA and 0.02% NaN3
storage stability :
The lyophilized antibody is stable for at least one year when stored at -20 degree C after reconstitution.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Peptide ELISA titer: 1:10,000-1:80,000. Western blot analysis: 1:200-1:1,000. Immunohistochemistry: 1:100-500. Optimal dilutions/concentrations should be determined by the end use.
other info1 :
Source Note: Rabbit polyclonal Cytokeratin-1 (1) antibody was raised against a peptide from the intermediate residues of human Cytokeratin-1 protein. Reactivity Note: Not yet tested in other species.
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
ncbi acc num :
NP_006112.3
ncbi gb acc num :
NM_006121
ncbi mol weight :
66,039 Da
ncbi pathways :
Corticotropin-releasing Hormone Pathway 920957!!Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway 169352
ncbi summary :
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]