catalog number :
MBS852131
products full name :
AICDA Antibody
products short name :
AICDA
other names :
single-stranded DNA cytosine deaminase; Single-stranded DNA cytosine deaminase; single-stranded DNA cytosine deaminase; cytidine aminohydrolase; epididymis secretory protein Li 284; integrated into Burkitt's lymphoma cell line Ramos; activation-induced cytidine deaminase; Activation-induced cytidine deaminase; Cytidine aminohydrolase
products gene name :
AICDA
other gene names :
AICDA; AICDA; AID; ARP2; CDA2; HIGM2; HEL-S-284; AID
uniprot entry name :
AICDA_HUMAN
reactivity :
Human, Mouse
form :
Lyophilized rabbit anti-AICDA purified by peptide affinity column containing 1% BSA and 0.02% NaN3
concentration :
100ug/200ul
storage stability :
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at -20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Peptide ELISA titer: 1:1,000-1:10,000. Western blot analysis: 1:200-1,000. Immunohistochemistry: 1:100-500. Optimal dilutions/concentrations should be determined by the end user.
other info1 :
Source Note: Rabbit polyclonal AICDA(1) antibody was raised against a 16 amino acid peptide corresponding to near the N terminal residues of Human AICDA. Reactivity Note: Not yet tested in other species.
other info2 :
Pathway: Activation-induced cytidine deaminase
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
ncbi acc num :
NP_065712.1
ncbi gb acc num :
NM_020661.2
ncbi mol weight :
22,614 Da
ncbi pathways :
IL4-mediated Signaling Events Pathway 137933!!Intestinal Immune Network For IgA Production Pathway 128760!!Intestinal Immune Network For IgA Production Pathway 128670!!Primary Immunodeficiency Pathway 83125!!Primary Immunodeficiency Pathway 537!!Salvage Pathways Of Pyrimidine Deoxyribonucleotides 142286!!Salvage Pathways Of Pyrimidine Ribonucleotides 142284
ncbi summary :
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009]