product summary
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company name :
MyBioSource
product type :
antibody
product name :
Claudin-4 (phospho Tyr208) Polyclonal Antibody
catalog :
MBS8520862
quantity :
0.1 mg
price :
280 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS8520862
products type :
Antibody
products full name :
Claudin-4 (phospho Tyr208) Polyclonal Antibody
products short name :
[Claudin-4]
products name syn :
[CLDN4; CPER; CPETR1; WBSCR8; Claudin-4; Clostridium perfringens enterotoxin receptor; CPE-R; CPE-receptor; Williams- Beuren syndrome chromosomal region 8 protein]
other names :
[claudin-4; Claudin-4; claudin-4; claudin 4; Clostridium perfringens enterotoxin receptor]
other gene names :
[CLDN4; CLDN4; CPER; CPE-R; CPETR; CPETR1; WBSCR8; hCPE-R; ; CPE-receptor]
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human
sequence length :
209
specificity :
Phospho-Claudin-4 (Y208) Polyclonal Antibody detects endogenous levels of Claudin-4 protein only when phosphorylated at Y208
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
form :
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
concentration :
1 mg/ml
storage stability :
Store at -20°C / 1 year.
tested application :
Immunohistochemistry (IHC) , ELISA (EIA)
app notes :
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications
other info1 :
Immunogen: Synthesized peptide derived from human Claudin-4 around the phosphorylation site of Y208
ncbi gi num :
4502877
ncbi acc num :
NP_001296.1
ncbi gb acc num :
NM_001305.4
uniprot acc num :
O14493
ncbi pathways :
Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cell Junction Organization Pathway (160966); Cell-Cell Communication Pathway (477132); Cell-cell Junction Organization Pathway (119532); Hepatitis C Pathway (173973); Hepatitis C Pathway (173907); Leukocyte Transendothelial Migration Pathway (83083); Leukocyte Transendothelial Migration Pathway (494); Tight Junction Pathway (83071)
ncbi summary :
The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013]
uniprot summary :
Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
size1 :
0.1 mg
price1 :
280 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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