catalog number :
MBS851956
products full name :
BNIP2 Antibody
products short name :
BNIP2
products name syn :
BCL2/adenovirus E1B 19-kDa protein-interacting 2; BCL2/adenovirus E1B 19kD interacting 2; BCL2/adenovirus E1B 19kD-interacting 2; BCL2/adenovirus E1B 19kDa interacting 2; BNIP-2; NIP2
other names :
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2; BCL2/adenovirus E1B 19 kDa protein-interacting protein 2; BCL2/adenovirus E1B 19 kDa protein-interacting protein 2; BCL2/adenovirus E1B 19kDa interacting protein 2
products gene name :
BNIP2
other gene names :
BNIP2; BNIP2; NIP2; BNIP-2; NIP2
uniprot entry name :
BNIP2_HUMAN
reactivity :
Human, Mouse
specificity :
BNIP2 antibody detects endogenous levels of total BNIP2 protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20 degree C for 1 year
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
WB: 1:500~1:1000, ELISA: 1:40000
other info2 :
Immunogen: The antiserum was produced against synthesized peptide derived from C-terminal of human BNIP2. Pathway: Cancer/Apoptosis
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
Boyd J.M., Cell 79:341-351(1994). Rieder M.J., Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases. The MGC Project Team; Genome Res. 14:2121-2127(2004). -----------------------------------------------------------------------------------------------------------------------------------
ncbi acc num :
NP_004321.2
ncbi gb acc num :
NM_004330.2
ncbi mol weight :
43,135 Da
ncbi pathways :
CDO In Myogenesis Pathway (160998); Developmental Biology Pathway (477129); Myogenesis Pathway (160997)
ncbi summary :
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. [provided by RefSeq, Mar 2011]
uniprot summary :
BNIP2: Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Apoptosis; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 15q22.2. Cellular Component: intracellular membrane-bound organelle; perinuclear region of cytoplasm; cytoplasm; nuclear envelope; cytosol. Molecular Function: identical protein binding; protein binding; calcium ion binding; GTPase activator activity. Biological Process: muscle cell differentiation; apoptosis; positive regulation of muscle cell differentiation; negative regulation of apoptosis; positive regulation of GTPase activity