catalog number :
MBS851931
products full name :
CHSY2 Antibody
products short name :
CHSY2
products name syn :
CHSS2; DKFZP434E0423; EC 2.4.1.175; EC 2.4.1.226
other names :
chondroitin sulfate synthase 2 isoform 2; Chondroitin sulfate synthase 2; chondroitin sulfate synthase 2; chondroitin-polymerizing factor; N-acetylgalactosaminyltransferase 2; chondroitin glucuronyltransferase 2; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; chondroitin polymerizing factor; Chondroitin glucuronyltransferase 2; Chondroitin-polymerizing factor; ChPF; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II; N-acetylgalactosaminyltransferase 2
products gene name :
CHSY2
other gene names :
CHPF; CHPF; CSS2; CHSY2; CSS2; ChPF
uniprot entry name :
CHSS2_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
CHSS2 antibody detects endogenous levels of total CHSS2 protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at -20 degree C for 1 year
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
app notes :
WB: 1:500~1:1000, IHC: 1:50~1:100, IF: 1:100~1:500, ELISA: 1:40000
other info2 :
Immunogen: The antiserum was produced against synthesized peptide derived from internal of human CHSS2. Pathway: Translation
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
Kitagawa H., J. Biol. Chem. 278:23666-23671(2003). Yada T., J. Biol. Chem. 278:30235-30247(2003). Clark H.F., Genome Res. 13:2265-2270(2003). ------------------------------------------------------------------------------------------------------------------------------------------
ncbi acc num :
NP_001182660.1
ncbi gb acc num :
NM_001195731.1
ncbi mol weight :
68,341 Da
ncbi pathways :
Chondroitin Sulfate Biosynthesis Pathway (645309); Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway (645308); Disease Pathway (530764); Glycogen Storage Diseases Pathway (980468); Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway (82982); Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway (356); Glycosaminoglycan Biosynthesis, Chondroitin Sulfate Backbone Pathway (413364); Glycosaminoglycan Biosynthesis, Chondroitin Sulfate Backbone Pathway (468251); Glycosaminoglycan Metabolism Pathway (645297); MPS I - Hurler Syndrome Pathway (685537)
uniprot summary :
CHPF: a type II transmembrane protein. May act as a specific activating factor for chondroitin synthase in chondroitin biosynthesis and polymerization. Protein type: Membrane protein, integral; EC 2.4.1.226; EC 2.4.1.175; Glycan Metabolism - chondroitin sulfate biosynthesis; Transferase. Chromosomal Location of Human Ortholog: 2q35. Cellular Component: Golgi membrane; mitochondrial matrix; integral to membrane; cytosol. Molecular Function: protein binding; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity; metal ion binding; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. Biological Process: chondroitin sulfate metabolic process; chondroitin sulfate biosynthetic process; glycosaminoglycan metabolic process; carbohydrate metabolic process; pathogenesis